OBJECTIVE: To study the chemical constituents of the sporoderm-broken spores of Ganoderma lucidum. METHODS: Chemical constituents were isolated and purified by silica gel and Sephadex LH-20 column chromatography. The structures were identified by means of physicochemical and spectral data. RESULTS: From the ethyl acetate extract of the material, eight compounds were isolated. Their structures were identified as ganoderic acid A (I), methyl ganoderate A (II), methyl ganoderate B (III), ganoderic acid C2 (IV), ganoderic acid G(V), ergosta-7,22-diene-3beta, 5alpha, 6beta-triol (VI), ergosterol peroxide (VII) and ergosta-7,22-diene-3beta-yl pentadecanoate (VIII), respectively. CONCLUSION: Compounds II, III, VII and VIII are isolated from the spores of G. lucidum for the first time.
OBJECTIVE: To study the chemical constituents of the sporoderm-broken spores of Ganoderma lucidum. METHODS: Chemical constituents were isolated and purified by silica gel and Sephadex LH-20 column chromatography. The structures were identified by means of physicochemical and spectral data. RESULTS: From the ethyl acetate extract of the material, eight compounds were isolated. Their structures were identified as ganoderic acid A (I), methyl ganoderate A (II), methyl ganoderate B (III), ganoderic acid C2 (IV), ganoderic acid G(V), ergosta-7,22-diene-3beta, 5alpha, 6beta-triol (VI), ergosterol peroxide (VII) and ergosta-7,22-diene-3beta-yl pentadecanoate (VIII), respectively. CONCLUSION: Compounds II, III, VII and VIII are isolated from the spores of G. lucidum for the first time.