Literature DB >> 18589195

Benign transient hyperphosphatasemia associated with Epstein-Barr virus enteritis in a pediatric liver transplant patient: a case report.

T Hranjec1, H Bonatti, A L Roman, C Sifri, S M Borowitz, B H Barnes, T R Flohr, T L Pruett, R G Sawyer, T M Schmitt.   

Abstract

Transient hyperphosphatasemia was found in a 3-year-old male liver transplant recipient. The condition was associated with diarrheal disease due to the Epstein-Barr virus (EBV). Immunosuppression was tapered and valganciclovir prescribed for 3 months, after which the diarrhea resolved and the EBV polymerase chain reaction assays became negative. After 6 months, alkaline phosphatase levels normalized. Isolated elevation of alkaline phosphatase in conjunction with enteric infection is a rare condition. No further diagnostic or therapeutic interventions except treatment of the underlying infection are needed, as this has been shown to be a benign, transient condition.

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Year:  2008        PMID: 18589195      PMCID: PMC3460270          DOI: 10.1016/j.transproceed.2008.04.011

Source DB:  PubMed          Journal:  Transplant Proc        ISSN: 0041-1345            Impact factor:   1.066


  25 in total

1.  Transient hyperphosphatasemia in a renal transplant patient.

Authors:  F Cachat; J P Guignard
Journal:  Acta Paediatr       Date:  1999-09       Impact factor: 2.299

2.  Regarding diarrhea in liver transplant recipients: etiology and management.

Authors:  I Stelzmueller; M Biebl; I Graziadei; S Wiesmayr; R Margreiter; H Bonatti
Journal:  Liver Transpl       Date:  2006-01       Impact factor: 5.799

3.  Infectious diarrhea in transplant recipients: current challenges and future directions.

Authors:  A K Subramanian; C L Sears
Journal:  Transpl Infect Dis       Date:  2007-12       Impact factor: 2.228

4.  Transient hyperphosphatasemia after pediatric liver transplantation.

Authors:  Cigdem Arikan; Mehmet Tayyip Arslan; Murat Kilic; Sema Aydogdu
Journal:  Pediatr Int       Date:  2006-08       Impact factor: 1.524

5.  A cluster of rotavirus enteritis in adult transplant recipients.

Authors:  I Stelzmueller; K M Dunst; P Hengster; H Wykypiel; W Steurer; S Wiesmayr; R Margreiter; H Bonatti
Journal:  Transpl Int       Date:  2005-04       Impact factor: 3.782

6.  An analysis of the OPTN/UNOS Liver Transplant Registry.

Authors:  Yasuro Futagawa; Paul I Terasaki
Journal:  Clin Transpl       Date:  2004

7.  Transient hyperphosphatasemia after organ transplantation in children.

Authors:  Bruno Ranchin; Florence Villard; Jean-Luc André; Isabelle Canterino; Marie-Hélène Said; Renée-Claude Boisson; Alain Lachaux; Louis David; Pierre Cochat
Journal:  Pediatr Transplant       Date:  2002-08

Review 8.  Percutaneous liver biopsy in clinical practice.

Authors:  Bandar Al Knawy; Mitchell Shiffman
Journal:  Liver Int       Date:  2007-11       Impact factor: 5.828

9.  A cause-specific hazard rate analysis of prognostic factors among 877 adults who received primary orthotopic liver transplantation.

Authors:  Jeffrey J Gaynor; Jang I Moon; Tomoaki Kato; Seigo Nishida; Gennaro Selvaggi; David M Levi; Eddie R Island; Nikolaos Pyrsopoulos; Debbie Weppler; Susan Ganz; Phillip Ruiz; Andreas G Tzakis
Journal:  Transplantation       Date:  2007-07-27       Impact factor: 4.939

10.  Rotavirus enteritis in solid organ transplant recipients: an underestimated problem?

Authors:  I Stelzmueller; S Wiesmayr; B R Swenson; M Biebl; H Goegele; R Margreiter; H Bonatti
Journal:  Transpl Infect Dis       Date:  2007-07-01       Impact factor: 2.228

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