| Literature DB >> 18589195 |
T Hranjec1, H Bonatti, A L Roman, C Sifri, S M Borowitz, B H Barnes, T R Flohr, T L Pruett, R G Sawyer, T M Schmitt.
Abstract
Transient hyperphosphatasemia was found in a 3-year-old male liver transplant recipient. The condition was associated with diarrheal disease due to the Epstein-Barr virus (EBV). Immunosuppression was tapered and valganciclovir prescribed for 3 months, after which the diarrhea resolved and the EBV polymerase chain reaction assays became negative. After 6 months, alkaline phosphatase levels normalized. Isolated elevation of alkaline phosphatase in conjunction with enteric infection is a rare condition. No further diagnostic or therapeutic interventions except treatment of the underlying infection are needed, as this has been shown to be a benign, transient condition.Entities:
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Year: 2008 PMID: 18589195 PMCID: PMC3460270 DOI: 10.1016/j.transproceed.2008.04.011
Source DB: PubMed Journal: Transplant Proc ISSN: 0041-1345 Impact factor: 1.066