| Literature DB >> 18586597 |
D Concolino1, G Muzzi, L Pisaturo, A Piccirillo, P Di Natale, Pietro Strisciuglio.
Abstract
To date the association between mucopolysaccharidosis (MPS) IIIA and precocious puberty has been found in only three polish patients. We observed two children affected by MPS IIIA with central precocious puberty (CPP) both treated with GnRH agonists. The occurrence of CPP in both patients with MPS IIIA suggests that it is necessary to look for an association between the two conditions. The follow-up of our two patients leads us to believe also that GnRH agonist treatment can have a beneficial effect on final height and probably on the improvement of behavioural problems.Entities:
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Year: 2008 PMID： 18586597 DOI： 10.1016/j.ejmg.2008.05.002
Source DB: PubMed Journal: Eur J Med Genet ISSN： 1769-7212 Impact factor: 2.708