| Literature DB >> 18586309 |
Antonio González-Martín1, Lucía González-Cortijo, Natalia Carballo, Juan F Garcia, Fernando Lapuente, Alejandro Rojo, Luis M Chiva.
Abstract
The role of neoadjuvant chemotherapy (NACT) in cervical cancer has been a matter of investigation over the last 20 years. A systematic review and meta-analysis of individual patient data (IPD) demonstrated that NACT followed by surgery is superior to radiotherapy alone in terms of overall survival. However, in spite of the results of the meta-analysis, NACT has not been adopted as the new standard of care. In the present paper, we review the reasons why NACT is still considered an investigational approach in cervical cancer.Entities:
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Year: 2008 PMID： 18586309 DOI： 10.1016/j.ygyno.2008.05.012
Source DB: PubMed Journal: Gynecol Oncol ISSN： 0090-8258 Impact factor: 5.482