Literature DB >> 18585729

Comprehensive two-dimensional high-performance liquid chromatography system with immobilized liposome chromatography column and reversed-phase column for separation of complex traditional Chinese medicine Longdan Xiegan Decoction.

Yun Wang1, Liang Kong, Xiaoyuan Lei, Lianghai Hu, Hanfa Zou, Ed Welbeck, S W Annie Bligh, Zhengtao Wang.   

Abstract

A comprehensive two-dimensional HPLC system with an immobilized liposome chromatography (ILC) column in conjunction with an RP column (in tandem) was developed for the screening and analysis of the membrane-permeable compounds in a traditional Chinese medicine prescription Longdan Xiegan Decoction (LXD). More than 50 components in LXD were resolved using the developed separation system. Eight flavonoids and two iridoids were identified interacting with the ILC column; a system that mimics biomembranes. The results show that the developed comprehensive two-dimensional chromatography system can be used for identifying membrane permeable natural products in complex matrixes such as extracts of traditional Chinese medicine prescriptions.

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Year:  2008        PMID： 18585729     DOI： 10.1016/j.chroma.2008.05.074

Source DB:  PubMed          Journal:  J Chromatogr A        ISSN： 0021-9673            Impact factor:   4.759


  7 in total

1.  Rapid separation and quantitation of curcuminoids combining pseudo two-dimensional liquid flash chromatography and NMR spectroscopy.

Authors:  G K Jayaprakasha; G A Nagana Gowda; Sixto Marquez; Bhimanagouda S Patil
Journal:  J Chromatogr B Analyt Technol Biomed Life Sci       Date:  2013-08-16       Impact factor: 3.205

Review 2.  High performance affinity chromatography and related separation methods for the analysis of biological and pharmaceutical agents.

Authors:  Chenhua Zhang; Elliott Rodriguez; Cong Bi; Xiwei Zheng; Doddavenkatana Suresh; Kyungah Suh; Zhao Li; Fawzi Elsebaei; David S Hage
Journal:  Analyst       Date:  2018-01-15       Impact factor: 4.616

Review 3.  Affinity chromatography: A review of trends and developments over the past 50 years.

Authors:  Elliott L Rodriguez; Saumen Poddar; Sazia Iftekhar; Kyungah Suh; Ashley G Woolfork; Susan Ovbude; Allegra Pekarek; Morgan Walters; Shae Lott; David S Hage
Journal:  J Chromatogr B Analyt Technol Biomed Life Sci       Date:  2020-08-14       Impact factor: 3.205

4.  Recent Advances in Supramolecular Affinity Separations: Affinity Chromatography and Related Methods.

Authors:  Ashley G Woolfork; Sazia Iftekhar; Susan Ovbude; Kyungah Suh; Sadia Sharmeen; Isaac Kyei; Jacob Jones; David S Hage
Journal:  Adv Chromatogr       Date:  2021       Impact factor: 0.400

Review 5.  Anti-inflammatory activity of traditional Chinese medicinal herbs.

Authors:  Min-Hsiung Pan; Yi-Shiou Chiou; Mei-Ling Tsai; Chi-Tang Ho
Journal:  J Tradit Complement Med       Date:  2011-10

6.  Identification and determination of the major constituents in traditional Chinese medicine Longdan Xiegan Pill by HPLC-DAD-ESI-MS.

Authors:  Hui Liu; Juan Su; Xu Liang; Xi Zhang; Ya-Jun He; Hai-Qiang Huang; Ji Ye; Wei-Dong Zhang
Journal:  J Pharm Anal       Date:  2012-01-30

7.  Fast Screening of Biomembrane-Permeable Compounds in Herbal Medicines Using Bubble-Generating Magnetic Liposomes Coupled with LC-MS.

Authors:  Xiaoting Gu; Dongwu Wang; Xin Wang; Youping Liu; Xin Di
Journal:  Molecules       Date:  2021-03-20       Impact factor: 4.411
  7 in total

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