Literature DB >> 18585345

Forging new ties between E. coli genes.

Trey Ideker1.   

Abstract

A recent study in Nature (Isalan et al., 2008) has examined the effects of systematically adding new transcriptional interactions in the bacterium Escherichia coli. Surprisingly, the majority of the engineered connections have no effect on growth, and in some cases the new connections enhance fitness. These findings reveal insights into the robustness and evolvability of gene networks.

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Year:  2008        PMID: 18585345      PMCID: PMC2806683          DOI: 10.1016/j.cell.2008.06.003

Source DB:  PubMed          Journal:  Cell        ISSN: 0092-8674            Impact factor:   41.582


  9 in total

1.  Serial regulation of transcriptional regulators in the yeast cell cycle.

Authors:  I Simon; J Barnett; N Hannett; C T Harbison; N J Rinaldi; T L Volkert; J J Wyrick; J Zeitlinger; D K Gifford; T S Jaakkola; R A Young
Journal:  Cell       Date:  2001-09-21       Impact factor: 41.582

Review 2.  Network biology: understanding the cell's functional organization.

Authors:  Albert-László Barabási; Zoltán N Oltvai
Journal:  Nat Rev Genet       Date:  2004-02       Impact factor: 53.242

Review 3.  Integrating physical and genetic maps: from genomes to interaction networks.

Authors:  Andreas Beyer; Sourav Bandyopadhyay; Trey Ideker
Journal:  Nat Rev Genet       Date:  2007-09       Impact factor: 53.242

4.  The cellular concentration of the sigma S subunit of RNA polymerase in Escherichia coli is controlled at the levels of transcription, translation, and protein stability.

Authors:  R Lange; R Hengge-Aronis
Journal:  Genes Dev       Date:  1994-07-01       Impact factor: 11.361

5.  Growth phase variation of integration host factor level in Escherichia coli.

Authors:  M D Ditto; D Roberts; R A Weisberg
Journal:  J Bacteriol       Date:  1994-06       Impact factor: 3.490

6.  The Escherichia coli Fis promoter is regulated by changes in the levels of its transcription initiation nucleotide CTP.

Authors:  Kimberly A Walker; Prabhat Mallik; Timothy S Pratt; Robert Osuna
Journal:  J Biol Chem       Date:  2004-09-22       Impact factor: 5.157

7.  Reverse two-hybrid and one-hybrid systems to detect dissociation of protein-protein and DNA-protein interactions.

Authors:  M Vidal; R K Brachmann; A Fattaey; E Harlow; J D Boeke
Journal:  Proc Natl Acad Sci U S A       Date:  1996-09-17       Impact factor: 11.205

8.  Evolvability and hierarchy in rewired bacterial gene networks.

Authors:  Mark Isalan; Caroline Lemerle; Konstantinos Michalodimitrakis; Carsten Horn; Pedro Beltrao; Emanuele Raineri; Mireia Garriga-Canut; Luis Serrano
Journal:  Nature       Date:  2008-04-17       Impact factor: 49.962

Review 9.  Synonymous codon usage in bacteria.

Authors:  M D Ermolaeva
Journal:  Curr Issues Mol Biol       Date:  2001-10       Impact factor: 2.081

  9 in total
  1 in total

1.  Protein evolution in yeast transcription factor subnetworks.

Authors:  Yong Wang; Eric A Franzosa; Xiang-Sun Zhang; Yu Xia
Journal:  Nucleic Acids Res       Date:  2010-05-13       Impact factor: 16.971

  1 in total

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