Literature DB >> 18583130

A regiospecific synthesis of a series of 1-sulfonyl azepinoindoles as potent 5-HT6 ligands.

Kevin G Liu1, Jennifer R Lo, Thomas A Comery, Guo Ming Zhang, Jean Y Zhang, Dianne M Kowal, Deborah L Smith, Li Di, Edward H Kerns, Lee E Schechter, Albert J Robichaud.   

Abstract

A regiospecific synthesis of a series of 1-sulfonyl azepinoindoles as potent 5-HT6 ligands is reported.

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Year:  2008        PMID： 18583130     DOI： 10.1016/j.bmcl.2008.06.030

Source DB:  PubMed          Journal:  Bioorg Med Chem Lett        ISSN： 0960-894X            Impact factor:   2.823


  3 in total

Review 1.  The medicinal chemistry of 5-HT6 receptor ligands with a focus on arylsulfonyltryptamine analogs.

Authors:  Richard A Glennon; Uma Siripurapu; Bryan L Roth; Renata Kolanos; Mikhail L Bondarev; Donald Sikazwe; Mase Lee; Małgorzata Dukat
Journal:  Curr Top Med Chem       Date:  2010       Impact factor: 3.295

2.  Antidepressant potential of nitrogen-containing heterocyclic moieties: An updated review.

Authors:  Nadeem Siddiqui; Sandhya Bawa; Ruhi Ali; Obaid Afzal; M Jawaid Akhtar; Bishmillah Azad; Rajiv Kumar
Journal:  J Pharm Bioallied Sci       Date:  2011-04

3.  Investigation of the structure requirement for 5-HT₆ binding affinity of arylsulfonyl derivatives: a computational study.

Authors:  Ming Hao; Yan Li; Hanqing Li; Shuwei Zhang
Journal:  Int J Mol Sci       Date:  2011-08-08       Impact factor: 5.923
  3 in total

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