OBJECTIVE: Self-mutilation is a severe symptom of diseases with varying etiologies. It can be observed in the context of mental retardation and after traumatic brain injury. Pharmacological treatment approaches often prove ineffective. CLINICAL PRESENTATION: We report the case of a 22-year-old woman with repetitive self-mutilating behavior in the mouth area after severe traumatic brain injury. RESULTS: Bilateral deep brain stimulation of the posterior hypothalamus was conducted and resulted in the complete elimination of self-mutilation during a 4-month observation period. CONCLUSION: This technical case report indicates that deep brain stimulation of the posterior hypothalamus could be a promising approach in the treatment of severe self-mutilating behavior.
OBJECTIVE: Self-mutilation is a severe symptom of diseases with varying etiologies. It can be observed in the context of mental retardation and after traumatic brain injury. Pharmacological treatment approaches often prove ineffective. CLINICAL PRESENTATION: We report the case of a 22-year-old woman with repetitive self-mutilating behavior in the mouth area after severe traumatic brain injury. RESULTS: Bilateral deep brain stimulation of the posterior hypothalamus was conducted and resulted in the complete elimination of self-mutilation during a 4-month observation period. CONCLUSION: This technical case report indicates that deep brain stimulation of the posterior hypothalamus could be a promising approach in the treatment of severe self-mutilating behavior.
Authors: Roberto Cordella; F Carella; A Franzini; C Marras; F Villani; G Messina; G Tringali; G Broggi Journal: Neurol Sci Date: 2010-02-05 Impact factor: 3.307
Authors: Clemens Neudorfer; Gavin J B Elias; Martin Jakobs; Alexandre Boutet; Jürgen Germann; Keshav Narang; Aaron Loh; Michelle Paff; Andreas Horn; Walter Kucharczyk; Wissam Deeb; Bryan Salvato; Leonardo Almeida; Kelly D Foote; Paul B Rosenberg; David F Tang-Wai; William S Anderson; Zoltan Mari; Francisco A Ponce; David A Wolk; Anna D Burke; Stephen Salloway; Marwan N Sabbagh; M Mallar Chakravarty; Gwenn S Smith; Constantine G Lyketsos; Michael S Okun; Andres M Lozano Journal: Brain Date: 2021-10-22 Impact factor: 13.501
Authors: William P Melega; Goran Lacan; Alessandra A Gorgulho; Eric J Behnke; Antonio A F De Salles Journal: PLoS One Date: 2012-01-25 Impact factor: 3.240
Authors: Osama A Abulseoud; Ulas M Camsari; Christina L Ruby; Khalid Mohamed; Noha M Abdel Gawad; Aimen Kasasbeh; Mehmet Y Yüksel; Doo-Sup Choi Journal: Int J Bipolar Disord Date: 2014-06-14
Authors: Flavia Venetucci Gouveia; Clement Hamani; Erich Talamoni Fonoff; Helena Brentani; Eduardo Joaquim Lopes Alho; Rosa Magaly Campêlo Borba de Morais; Aline Luz de Souza; Sérgio Paulo Rigonatti; Raquel C R Martinez Journal: Neurosurgery Date: 2019-07-01 Impact factor: 4.654