Literature DB >> 18580258

Femtosecond laser-assisted lamellar keratoplasty: early results.

Luigi Mosca1, Romina Fasciani, Ciro Tamburelli, Luca Buzzonetti, Laura Guccione, Erika Mandarà, Emilio Balestrazzi.   

Abstract

PURPOSE: To evaluate the outcomes and safety of lamellar keratoplasty (LK) assisted by a femtosecond laser.
METHODS: Twenty-one eyes of 21 patients affected by different corneal pathologies (5 posttraumatic corneal scar, 3 postkeratitis corneal leucoma, and 13 keratoconus) underwent LK procedures by using a femtosecond laser. The mean thinnest corneal thickness, evaluated with ultrasound corneal pachymetry and with confocal microscopy, was 434.19 +/- 62.60 (SD) microm (range, 333-548 microm). Mean preoperative uncorrected visual acuity was 0.09 +/- 0.28 SD and mean preoperative best spectacle-corrected visual acuity was 0.28 +/- 0.15 SD. A femtosecond laser was used to perform corneal cuts on both donor and recipient corneas. The donor corneal lamella diameters were 0.20-mm larger and thicker than the recipient to restore a physiologic corneal thickness and shape: mean donor diameter was 8.34 +/- 0.28 mm (range, 8.2-8.7 mm) and mean thickness was 352 +/- 40.27 microm (range, 220-400 microm). Mean follow-up was 20.86 +/- 5.76 months (range, 12-30 months).
RESULTS: Early postoperative evaluation showed a clear graft in all cases. A normal corneal pattern topography and a physiologic thickness (mean corneal pachymetry, 542.48 +/- 33.20 microm) and transparency were restored. Twelve months after surgery, the mean postoperative uncorrected visual acuity was 0.45 +/- 0.34 SD, and the mean best spectacle-corrected visual acuity was 0.63 +/- 0.16 SD.
CONCLUSIONS: Although the numbers in our study are small, our early results indicate that femtosecond laser-assisted lamellar keratoplasty shows promise as a safe and effective surgical choice in the treatment of various corneal pathologies.

Entities:  

Mesh:

Year:  2008        PMID: 18580258     DOI: 10.1097/ICO.0b013e31816736b1

Source DB:  PubMed          Journal:  Cornea        ISSN: 0277-3740            Impact factor:   2.651


  12 in total

Review 1.  Surgical strategies to improve visual outcomes in corneal transplantation.

Authors:  M S Rajan
Journal:  Eye (Lond)       Date:  2014-01-03       Impact factor: 3.775

2.  Interface quality of different corneal lamellar-cut depths for femtosecond laser-assisted lamellar anterior keratoplasty.

Authors:  Chenxing Zhang; Matthew Bald; Maolong Tang; Yan Li; David Huang
Journal:  J Cataract Refract Surg       Date:  2015-03-04       Impact factor: 3.351

3.  Comparison of long-term results after manual and femtosecond assisted corneal trephination in deep anterior lamellar keratoplasty for keratoconus.

Authors:  Hua Li; Min Chen; Yan-Ling Dong; Jing Zhang; Xian-Li Du; Jun Cheng; Hua Gao; Li-Xin Xie
Journal:  Int J Ophthalmol       Date:  2020-04-18       Impact factor: 1.779

4.  Deep Laser-Assisted Lamellar Anterior Keratoplasty With Microkeratome-Cut Grafts.

Authors:  Hideaki Yokogawa; Maolong Tang; Yan Li; Liang Liu; Winston Chamberlain; David Huang
Journal:  Cornea       Date:  2016-05       Impact factor: 2.651

5.  Femtosecond laser-assisted in situ keratomileusis for the correction of residual ametropia after deep anterior lamellar keratoplasty: a pilot investigation.

Authors:  A Balestrazzi; A Balestrazzi; F Menicacci; G Cartocci; F Menicacci; P Michieletto; E Balestrazzi
Journal:  Eye (Lond)       Date:  2017-04-07       Impact factor: 3.775

6.  In vivo confocal microscopic evaluation of corneal wound healing after femtosecond laser-assisted keratoplasty.

Authors:  Roni M Shtein; Kurt H Kelley; David C Musch; Alan Sugar; Shahzad I Mian
Journal:  Ophthalmic Surg Lasers Imaging       Date:  2012-02-16

7.  Outcomes of femtosecond laser-assisted mushroom-configuration keratoplasty in advanced keratoconus.

Authors:  S S M Fung; F Aiello; V Maurino
Journal:  Eye (Lond)       Date:  2016-01-22       Impact factor: 3.775

8.  Femtosecond laser-assisted deep anterior lamellar keratoplasty for keratoconus and keratectasia.

Authors:  Yan Lu; Yu-Hua Shi; Li-Ping Yang; Yi-Rui Ge; Xiang-Fei Chen; Yan Wu; Zhen-Ping Huang
Journal:  Int J Ophthalmol       Date:  2014-08-18       Impact factor: 1.779

9.  Sutureless femtosecond anterior lamellar keratoplasty: a 1-year follow-up study.

Authors:  Rohit Shetty; Harsha Nagaraja; Himabindu Veluri; Yathish Shivanna; Thungappa Kugar; Rudy Nujits; Bhujang Shetty
Journal:  Indian J Ophthalmol       Date:  2014-09       Impact factor: 1.848

Review 10.  Current techniques of lamellar keratoplasty for keratoconus.

Authors:  Leopoldo Spadea; Victoria De Rosa
Journal:  Saudi Med J       Date:  2016-02       Impact factor: 1.484

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