Literature DB >> 18580252

Eye bank survey of surgeons using precut donor tissue for descemet stripping automated endothelial keratoplasty.

Anna S Kitzmann1, Kenneth M Goins, Cynthia Reed, Lissa Padnick-Silver, Marian S Macsai, John E Sutphin.   

Abstract

PURPOSE: To assess surgeon satisfaction with precut corneal tissue from 1 eye bank for Descemet stripping automated endothelial keratoplasty (DSAEK). Surgical techniques and predictors of procedural success were also examined.
METHODS: A 19-question survey was completed by 53 surgeons around the United States for 197 DSAEK cases using prepared corneal allograft tissue from the Iowa Lions Eye Bank. Surgeries were performed between April 1 and December 31, 2006; surveys were completed retrospectively within a few weeks of surgery.
RESULTS: Tissue was found to be acceptable in 98% of DSAEK cases reported. Difficulties with precut tissue (eg, lack of anterior cap adherence to the posterior lamella, not visible or decentered central dot, anterior edge undermining) were reported in approximately 10% of cases. A rebubbling procedure was performed in 23% of cases for donor dislocations. The donor lenticule adhered, with resulting corneal deturgescence, in 86% of cases. Surgeons declared a successful procedure in 92% of cases. Of the 14 unsuccessful cases, donor tissue quality was the underlying etiology in only 1 case. Procedural success rates were related to surgeon experience (P = 0.002), lenticule adherence after only 1 anterior chamber air bubble (P = 0.005), no small perforations to release fluid (P = 0.005), and the presence of corneal deturgescence (P = 0.002).
CONCLUSIONS: The use of precut tissue for DSAEK is not associated with increased risk of complications related to tissue preparation. With standardization of precutting donor tissue, safety of DSAEK surgery may be improved while increasing surgeon efficiency.

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Year:  2008        PMID: 18580252     DOI: 10.1097/QAI.0b013e31815e4011

Source DB:  PubMed          Journal:  Cornea        ISSN: 0277-3740            Impact factor:   2.651


  11 in total

1.  A presentation of culture-positive corneal donors and the effect on clinical outcomes.

Authors:  Aida Hajjar Sesé; Jens Lindegaard; Hanne Olsen Julian; Klavs Højgaard-Olsen; Niels Frimodt Møller; Steffen Heegaard
Journal:  Graefes Arch Clin Exp Ophthalmol       Date:  2018-11-30       Impact factor: 3.117

Review 2.  Corneal endothelial autocrine trophic factor VIP in a mechanism-based strategy to enhance human donor cornea preservation for transplantation.

Authors:  Shay-Whey Margaret Koh
Journal:  Exp Eye Res       Date:  2011-10-25       Impact factor: 3.467

3.  Comparative study of descemet stripping automated endothelial keratoplasty donor preparation by Moria CBm microkeratome, horizon microkeratome, and Intralase FS60.

Authors:  V Vinod Mootha; Ellen Heck; Steven M Verity; W Matthew Petroll; Neema Lakshman; Orkun Muftuoglu; R Wayne Bowman; James P McCulley; H Dwight Cavanagh
Journal:  Cornea       Date:  2011-03       Impact factor: 2.651

4.  Excimer laser smoothing of endothelial keratoplasty grafts.

Authors:  Catherine Cleary; Ying Liu; Maolong Tang; Yan Li; Christopher Stoeger; David Huang
Journal:  Cornea       Date:  2012-04       Impact factor: 2.651

5.  Descemet's stripping automated endothelial keratoplasty outcomes compared with penetrating keratoplasty from the Cornea Donor Study.

Authors:  Marianne O Price; Mark Gorovoy; Beth A Benetz; Francis W Price; Harry J Menegay; Sara M Debanne; Jonathan H Lass
Journal:  Ophthalmology       Date:  2010-01-19       Impact factor: 12.079

6.  Preparation and Thickness Profile of Endothelial Keratoplasty Lenticules from Donated Whole Eyes with Previous Photorefractive Keratectomy.

Authors:  Mozhgan Rezaei Kanavi; Pejman Fahim; Mohsen Rahmanian; Tahereh Chamani; Bahar Kheiri; Sahar Balagholi; Mohammad Ali Javadi
Journal:  J Ophthalmic Vis Res       Date:  2017 Oct-Dec

7.  Eye bank prepared versus surgeon cut endothelial graft tissue for Descemet membrane endothelial keratoplasty: An observational study.

Authors:  Marie Regnier; Céline Auxenfans; Delphine Maucort-Boulch; Anne-Sophie Marty; Odile Damour; Carole Burillon; Viridiana Kocaba
Journal:  Medicine (Baltimore)       Date:  2017-05       Impact factor: 1.889

8.  Evaluation of interface quality in organ-cultured lamellar corneal transplants.

Authors:  Armin Wolf; Burkhard von Jagow; Daniel Kook; Elisabeth M Messmer; Carlo A Lackerbauer; Anselm Kampik; Thomas Kohnen; Martin Grueterich
Journal:  Clin Ophthalmol       Date:  2012-07-17

9.  A cost-minimization analysis of tissue-engineered constructs for corneal endothelial transplantation.

Authors:  Tien-En Tan; Gary S L Peh; Benjamin L George; Howard Y Cajucom-Uy; Di Dong; Eric A Finkelstein; Jodhbir S Mehta
Journal:  PLoS One       Date:  2014-06-20       Impact factor: 3.240

10.  Cost Minimization Analysis of Precut Cornea Grafts in Descemet Stripping Automated Endothelial Keratoplasty.

Authors:  Kai-Ling Yong; Hai V Nguyen; Howard Y Cajucom-Uy; Valencia Foo; Donald Tan; Eric A Finkelstein; Jodhbir S Mehta
Journal:  Medicine (Baltimore)       Date:  2016-02       Impact factor: 1.889

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