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Literature DB >> 1857761

Repair of damage caused by UV- and X-irradiation in the amoeboflagellate Naegleria gruberi.

Abstract

Cysts of Naegleria gruberi have a normal UV- and an extremely high X-ray resistance compared to other protozoans. Caffeine and 3-aminobenzamide applied to excysting amoeba after irradiation in the encysted state (UV and X-rays) by feeding with drug-containing bacteria increased lethality, while fractionated irradiation (UV) and liquid-holding (UV and X-rays) increased survival. Illumination with visible light after UV-irradiation restored almost 100% viability. The results are discussed in regard to the activity of repair mechanisms.

Entities: Chemical Disease Species

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Year: 1991 PMID： 1857761 DOI： 10.1007/bf01219346

Source DB: PubMed Journal: Radiat Environ Biophys ISSN： 0301-634X Impact factor: 1.925

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References

19 in total

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Authors: I Ceccherini; N Loprieno; I Sbrana
Journal: Mutagenesis Date: 1988-01 Impact factor: 3.000

Repair of damage caused by UV- and X-irradiation in the amoeboflagellate Naegleria gruberi.

1. Enhancement of postreplication repair in Chinese hamster cells.

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