Literature DB >> 18575975

Comparative efficacy of diminazene diaceturate and diminazene aceturate for the treatment of babesiosis in horses.

Hamad Bin Rashid1, Mamoona Chaudhry, Haroon Rashid, Khalid Pervez, Muhammad Arif Khan, Asim Khalid Mahmood.   

Abstract

The present work was conducted to study the comparative efficacy of two anti-protozoan (babesicidal) drugs on the recovery and health of horses. A total of 80 horses, showing typical clinical symptoms of the disease, were selected for this study; the presence of babesiosis was confirmed through blood smear examination. These animals were divided into two groups i.e. A and B. Horses of Group A, were treated with diminazene diaceturate, while horses of Group B were treated with diminazene aceturate. Efficacy of the drugs was determined by the reversal of clinical signs and a negative blood smear examination. The efficacy of diminazene diaceturate was demonstrated to be 80% while diminazene aceturate was found to have 90% efficacy against babesiosis.

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Year:  2007        PMID: 18575975     DOI: 10.1007/s11250-007-9121-2

Source DB:  PubMed          Journal:  Trop Anim Health Prod        ISSN: 0049-4747            Impact factor:   1.559


  7 in total

1.  In vitro cultivation of Babesia equi: detection of carrier animals and isolation of parasites.

Authors:  E Zweygarth; M C Just; D T De Waal
Journal:  Onderstepoort J Vet Res       Date:  1997-03       Impact factor: 1.792

2.  Outbreaks of babesiosis in domestic livestock in the eastern region of the Sudan.

Authors:  A A Mohamed; I A Yagoub
Journal:  Trop Anim Health Prod       Date:  1990-05       Impact factor: 1.559

Review 3.  Chemotherapy against babesiosis.

Authors:  Henri J Vial; A Gorenflot
Journal:  Vet Parasitol       Date:  2006-02-28       Impact factor: 2.738

Review 4.  Equine piroplasmosis: a review.

Authors:  D T de Waal
Journal:  Br Vet J       Date:  1992 Jan-Feb

5.  Prevalence of equine piroplasmosis in Central Mongolia.

Authors:  A Avarzed; D T De Waal; I Igarashi; A Saito; T Oyamada; Y Toyoda; N Suzuki
Journal:  Onderstepoort J Vet Res       Date:  1997-06       Impact factor: 1.792

Review 6.  Equine piroplasmosis an update on diagnosis, treatment and prevention.

Authors:  A Brüning
Journal:  Br Vet J       Date:  1996-03

7.  Chemotherapy of CNS-trypanosomiasis: the combined use of diminazene aceturate or pentamidine with DL-alpha-difluoromethylornithine (DFMO).

Authors:  F W Jennings
Journal:  Trop Med Parasitol       Date:  1992-06
  7 in total
  4 in total

1.  Use of a doxycycline-enrofloxacin-metronidazole combination with/without diminazene diaceturate to treat naturally occurring canine babesiosis caused by Babesia gibsoni.

Authors:  Ming-Yu Lin; Hui-Pi Huang
Journal:  Acta Vet Scand       Date:  2010-04-24       Impact factor: 1.695

2.  Prevalence of Theileria equi, Babesia caballi, and Anaplasma phagocytophilum in horses from the north of Portugal.

Authors:  Ana J Ribeiro; Luís Cardoso; José M Maia; Teresa Coutinho; Mário Cotovio
Journal:  Parasitol Res       Date:  2013-04-17       Impact factor: 2.289

3.  Bumped kinase inhibitor prohibits egression in Babesia bovis.

Authors:  Monica J Pedroni; Rama Subba Rao Vidadala; Ryan Choi; Katelyn R Keyloun; Molly C Reid; Ryan C Murphy; Lynn K Barrett; Wesley C Van Voorhis; Dustin J Maly; Kayode K Ojo; Audrey O T Lau
Journal:  Vet Parasitol       Date:  2015-11-05       Impact factor: 2.738

Review 4.  Babesia gibsoni Infection in Dogs-A European Perspective.

Authors:  Oliwier Teodorowski; Marcin Kalinowski; Dagmara Winiarczyk; Banu Dokuzeylül; Stanisław Winiarczyk; Łukasz Adaszek
Journal:  Animals (Basel)       Date:  2022-03-14       Impact factor: 2.752

  4 in total

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