Literature DB >> 18575798

Histomorphological analysis of the urogenital diaphragm in elderly women: a cadaver study.

C Betschart1, D Scheiner, C Maake, M Vich, L Slomianka, D Fink, D Perucchini.   

Abstract

The objective of this study was to describe the histomorphological structure of the urogenital diaphragm in elderly women using a modern morphometric procedure. Biopsies were taken from the posterior margin of the urogenital diaphragm of 22 female cadavers (mean age, 87 years) using a 60-mm punch. Hematoxylin/eosin and Goldner sections were analyzed with the Cavalieri estimator. The mean thickness of the urogenital diaphragm was 5.5 mm. The main component was connective tissue. All biopsies contained smooth muscle. Eighteen biopsies contained more smooth muscle than striated muscle. In six of 22 biopsies, no striated muscle was found. The ratio of striated to smooth muscle to connective tissue was 1:2.3:13.3. Muscle fibers were dispersed in all parts of the urogenital diaphragm. The urogenital diaphragm of elderly women mainly consists of connective tissue. Smooth muscle was also found but to a lesser extent. The frequently used English term "perineal membrane" for the urogenital diaphragm is justified and well describes our findings in elderly women.

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Year:  2008        PMID: 18575798     DOI: 10.1007/s00192-008-0669-9

Source DB:  PubMed          Journal:  Int Urogynecol J Pelvic Floor Dysfunct


  23 in total

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Authors:  M Pandit; J O DeLancey; J A Ashton-Miller; J Iyengar; M Blaivas; D Perucchini
Journal:  Obstet Gynecol       Date:  2000-06       Impact factor: 7.661

2.  Age effects on urethral striated muscle. II. Anatomic location of muscle loss.

Authors:  Daniele Perucchini; John O L DeLancey; James A Ashton-Miller; Andrzej Galecki; Gabriel N Schaer
Journal:  Am J Obstet Gynecol       Date:  2002-03       Impact factor: 8.661

3.  Histology of the connection between the vagina and levator ani muscles. Implications for urinary tract function.

Authors:  J O DeLancey; R A Starr
Journal:  J Reprod Med       Date:  1990-08       Impact factor: 0.142

4.  Myogenic changes of the levator ani muscle in premenopausal women: the impact of vaginal delivery and age.

Authors:  T Dimpfl; C Jaeger; W Mueller-Felber; C Anthuber; A Hirsch; R Brandmaier; B Schuessler
Journal:  Neurourol Urodyn       Date:  1998       Impact factor: 2.696

5.  Levator ani muscle morphology and recurrent genuine stress incontinence.

Authors:  E Hanzal; E Berger; H Koelbl
Journal:  Obstet Gynecol       Date:  1993-03       Impact factor: 7.661

6.  The striated urogenital sphincter muscle in the female.

Authors:  T M Oelrich
Journal:  Anat Rec       Date:  1983-02

7.  The dispute about the external sphincter and the urogenital diaphragm.

Authors:  W Dorschner; M Biesold; F Schmidt; J U Stolzenburg
Journal:  J Urol       Date:  1999-12       Impact factor: 7.450

8.  Histochemical and contractile properties of striated muscles of urethra and levator ani of dogs and sheep.

Authors:  Xinmin Chen; Kate E Creed
Journal:  Neurourol Urodyn       Date:  2004       Impact factor: 2.696

9.  Transvaginal repair of anterior and posterior compartment prolapse with Atrium polypropylene mesh.

Authors:  Peter L Dwyer; Barry A O'Reilly
Journal:  BJOG       Date:  2004-08       Impact factor: 6.531

10.  The pathogenesis of genitourinary prolapse and stress incontinence of urine. A histological and histochemical study.

Authors:  S A Gilpin; J A Gosling; A R Smith; D W Warrell
Journal:  Br J Obstet Gynaecol       Date:  1989-01
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  4 in total

1.  Dilemmas in Management of the Geriatric Bladder.

Authors:  S M Hartigan; W S Reynolds; P P Smith
Journal:  Curr Bladder Dysfunct Rep       Date:  2019-11-13

2.  Novel 3D MRI technique to measure perineal membrane structural changes with pregnancy and childbirth: Technique development and measurement feasibility.

Authors:  Fernanda Pipitone; Carolyn W Swenson; John O L DeLancey; Luyun Chen
Journal:  Int Urogynecol J       Date:  2021-04-24       Impact factor: 1.932

Review 3.  A current perspective on geriatric lower urinary tract dysfunction.

Authors:  Ha Bum Jung; Hyung Jee Kim; Sung Tae Cho
Journal:  Korean J Urol       Date:  2015-03-30

Review 4.  The urethral rhabdosphincter, levator ani muscle, and perineal membrane: a review.

Authors:  Nobuyuki Hinata; Gen Murakami
Journal:  Biomed Res Int       Date:  2014-04-27       Impact factor: 3.411

  4 in total

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