Transient splenial DWI abnormality of the corpus callosum during a stroke-like episode.

Focal imaging abnormalities of the corpus callosum are rare but have been described in various clinical conditions. Because the MRI appearance may mimic acute stroke, clinicians have to be aware of differential diagnoses. We report a patient with a stroke-like episode and transient hypersignal in diffusion with decreased ADC values of the corpus callosum in a setting of sepsis due to a Klebsiella pneumoniae infection. This stroke mimic may be due to an inflammatory process and should be recognized because of therapeutic implications.