Literature DB >> 18573434

Intrathoracic lipomas: their clinicopathological behaviors are not as straightforward as expected.

Hiroyuki Sakurai1, Masahiro Kaji, Kazuto Yamazaki, Keiichi Suemasu.   

Abstract

BACKGROUND: Lipomas are a common type of benign tumor, and may involve numerous sites. They are common in the subcutaneous region of the upper back, neck, and shoulder, but are rarely seen in the thoracic cavity. Intrathoracic lipomas are a type of deep-seated lipoma, unlike subcutaneous lipomas. Due to the rarity of intrathoracic lipomas, little is known about their clinicopathological features.
METHODS: We conducted a retrospective review of the clinicopathological records of 10 patients who had undergone surgical resection for intrathoracic lipomas during a 16-year period (1991 to 2006).
RESULTS: There were 9 men and 1 woman with a mean age of 57.9 years. The number of lesions was one in 9 patients and two in 1 patient. Symptoms caused by the tumor were seen in only one patient. Radiographically, the tumors showed well-defined, homogeneous, and fatty density masses/nodules. Intrathoracic lipomas were most frequently seen in the parietal pleura. The resected tumor size ranged from 1.0 to 6.0 cm. Pathologically, three lesions showed an infiltrating type in which mature fat cells were seen between and within muscle or nerve fascicles. One of these three ended in an incomplete resection because the tumor infiltrated the brachial plexus. One patient had a recurrent tumor arising from a resected margin.
CONCLUSIONS: Intrathoracic lipomas should be surgically resected if they are detected, because the possibility of liposarcoma or infiltrating development of the tumor cannot be excluded preoperatively. We think that surgical resection of the tumor, rather than conservative management by close observation alone, is a safer treatment.

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Year:  2008        PMID: 18573434     DOI: 10.1016/j.athoracsur.2008.03.052

Source DB:  PubMed          Journal:  Ann Thorac Surg        ISSN: 0003-4975            Impact factor:   4.330


  15 in total

1.  Spindle cell lipoma: a rare tumor of the mediastinum.

Authors:  Elvira La Mantia; Renato Franco; Raffaele Rocco; Gaetano Rocco
Journal:  J Thorac Dis       Date:  2013-08       Impact factor: 2.895

2.  Giant intrathoracic lipoma presenting as a lump in the supraclavicular fossa.

Authors:  Manaf Khatib; Mark G Soldin
Journal:  Ann R Coll Surg Engl       Date:  2010-06-07       Impact factor: 1.891

3.  Pleural lipoma clinically mimicking the presentation of superior sulcus tumour upon initial evaluation.

Authors:  Lisa N Glass; Hannah Goulart; Keith D Mortman; Jalil Ahari
Journal:  BMJ Case Rep       Date:  2017-12-07

4.  Deep-seated intramuscular lipoma penetrates the intercostal muscle.

Authors:  Jinwook Hwang; Won-Min Jo; Byoung-Ju Min; Jae Seung Shin
Journal:  J Thorac Dis       Date:  2015-10       Impact factor: 2.895

Review 5.  Parietal pleura lipoma: a rare intrathoracic tumor.

Authors:  Abdelfettah Zidane; Fouad Atoini; Adil Arsalane; Akram Traibi; Massime Hammoumi; Fayçal Ouariachi; Mohamed Oukabli; El Hassane Kabiri
Journal:  Gen Thorac Cardiovasc Surg       Date:  2011-05-06

6.  Pleural and Mediastinal Lipomatosis with Subpleural Fat as a Mimicker of Pleural Effusion- A Rare Case Report.

Authors:  Navkiran Kaur; Jasvir Singh; Samrin Haq; Sugandha Garg; Simmi Bhatnagar
Journal:  J Clin Diagn Res       Date:  2017-07-01

7.  Subpleural lipoma: Management of a rare intrathoracic tumor.

Authors:  Timothy Sakellaridis; Ioannis Panagiotou; Stylianos Gaitanakis; Stamatis Katsenos
Journal:  Int J Surg Case Rep       Date:  2013-03-14

Review 8.  The rare mediastinal lipoma: a postmortem case report.

Authors:  Yehia M A H Marreez; William Roy; Rouel Roque; Emmett Findlay
Journal:  Int J Clin Exp Pathol       Date:  2012-10-20

9.  Intrathoracic giant pleural lipoma: case report and review of the literature.

Authors:  Ming Chen; Jun Yang; Lei Zhu; Heng Zhao
Journal:  J Cardiothorac Surg       Date:  2013-10-11       Impact factor: 1.637

10.  Giant Right Intrathoracic Myxoid Fusocellular Lipoma.

Authors:  Petre V H Botianu; Anda Mihaela Cerghizan; Alexandru M Botianu
Journal:  Case Rep Pulmonol       Date:  2015-10-05
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