Literature DB >> 18573120

Postoperative PTH measurement facilitates day 1 discharge after total thyroidectomy.

Simon Grodski1, Catharina Ihre Lundgren, Stan Sidhu, Mark Sywak, Leigh Delbridge.   

Abstract

OBJECTIVE: A new protocol for postoperative calcium management was developed with the aim of achieving an increase in the proportion of patients being safely discharged on the first postoperative day. We present our experience with the first 50 patients treated under this new protocol. PATIENTS AND
DESIGN: A cohort study was performed involving the first 50 patients admitted for total or completion thyroidectomy, those data were then compared with a control group. Intact PTH (iPTH) was measured at 4-h postoperatively and patients with iPTH in the normal range were discharged on the first postoperative day.
RESULTS: Mean age and sex distribution were similar in both groups. Mean lowest postoperative corrected calcium levels in the study group were 2.19 mmol/l and 2.15 mmol/l in the control group (P = 0.24). Parathyroid auto-transplantation was associated with low PTH levels (risk ratio = 0.49). Over 50% of patients (n = 27) were successfully discharged on the first postoperative day in the study group and no patient required readmission. Length of stay was significantly shorter in the study group, mean 1.64 vs. 2.20 days (P < 0.05).
CONCLUSION: The use of iPTH accurately predicts hypocalcaemia after total thyroidectomy and can be used to facilitate safe early discharge for patients.

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Year:  2009        PMID: 18573120     DOI: 10.1111/j.1365-2265.2008.03317.x

Source DB:  PubMed          Journal:  Clin Endocrinol (Oxf)        ISSN: 0300-0664            Impact factor:   3.478


  11 in total

Review 1.  Management Guidelines for Children with Thyroid Nodules and Differentiated Thyroid Cancer.

Authors:  Gary L Francis; Steven G Waguespack; Andrew J Bauer; Peter Angelos; Salvatore Benvenga; Janete M Cerutti; Catherine A Dinauer; Jill Hamilton; Ian D Hay; Markus Luster; Marguerite T Parisi; Marianna Rachmiel; Geoffrey B Thompson; Shunichi Yamashita
Journal:  Thyroid       Date:  2015-07       Impact factor: 6.568

2.  Combining early postoperative parathyroid hormone and serum calcium levels allows for an efficacious selective post-thyroidectomy supplementation treatment.

Authors:  Marco Raffaelli; Carmela De Crea; Cinzia Carrozza; Gerardo D'Amato; Cecilia Zuppi; Rocco Bellantone; Celestino P Lombardi
Journal:  World J Surg       Date:  2012-06       Impact factor: 3.352

3.  One-Hour Postoperative Parathyroid Hormone Levels Do Not Reliably Predict Hypocalcemia After Thyroidectomy.

Authors:  Zeyad Sahli; Alireza Najafian; Stacie Kahan; Eric B Schneider; Martha A Zeiger; Aarti Mathur
Journal:  World J Surg       Date:  2018-07       Impact factor: 3.352

4.  Early Discharge and Selective Calcium Supplementation after Thyroidectomy Based on Post-Operative Day 1 Parathormone and Calcium Level: A Prospective Study.

Authors:  Suganya Sekar; Antonisamy Belavendra; Paul M Jacob
Journal:  Indian J Endocrinol Metab       Date:  2020-08-27

5.  Unexpected Benefits in Single Institution Experience With Successful Implementation of a Standardized Perioperative Protocol in Pediatric Thyroidectomy.

Authors:  Kristina Cossen; Matthew T Santore; Kara K Prickett; Steven L Goudy; Kurt F Heiss; Kanika Shanker; Adina L Alazraki; Briana C Patterson
Journal:  Pediatr Qual Saf       Date:  2022-06-14

6.  Preventing postoperative hypocalcemia in patients with Graves disease: a prospective study.

Authors:  Sarah C Oltmann; Andrew V Brekke; David F Schneider; Sarah C Schaefer; Herbert Chen; Rebecca S Sippel
Journal:  Ann Surg Oncol       Date:  2014-09-12       Impact factor: 5.344

7.  The impact of age and oral calcium and vitamin D supplements on postoperative hypocalcemia after total thyroidectomy. A prospective study.

Authors:  Salvatore Tolone; Ruggiero Roberto; Gianmattia del Genio; Luigi Brusciano; Domenico Parmeggiani; Vincenzo Amoroso; Giuseppina Casalino; Ignazio Verde; Alfonso Bosco; Antonio D'Alessandro; Raffaele Pirozzi; Gianluca Rossetti; Paolo Limongelli; Ludovico Docimo
Journal:  BMC Surg       Date:  2013-10-08       Impact factor: 2.102

8.  An intact parathyroid hormone-based protocol for the prevention and treatment of symptomatic hypocalcemia after thyroidectomy.

Authors:  Yvette Carter; Herbert Chen; Rebecca S Sippel
Journal:  J Surg Res       Date:  2013-10-08       Impact factor: 2.192

9.  Role of postoperative vitamin D and/or calcium routine supplementation in preventing hypocalcemia after thyroidectomy: a systematic review and meta-analysis.

Authors:  Amal Alhefdhi; Haggi Mazeh; Herbert Chen
Journal:  Oncologist       Date:  2013-05-01

10.  Usefulness of pre- and post-operative calcium and Vitamin D supplementation in prevention of hypocalcemia after total thyroidectomy: A randomized controlled trial.

Authors:  Sumiya Jaan; Ashish Sehgal; Rauf Ahmad Wani; Muneer Ahmad Wani; Khursheed Alam Wani; Bashir Ahmad Laway
Journal:  Indian J Endocrinol Metab       Date:  2017 Jan-Feb
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