OBJECTIVE: The purpose of this study was to determine if early response predicted remission at the end of a controlled trial. METHOD:Eighty adolescents with bulimia nervosa participated in an RCT comparing family-based treatment and individual supportive psychotherapy. Response to treatment was assessed via self-report of bingeing and purging. Remission was defined as abstinence from bingeing and purging for the last 28 days and measured by investigator-based interview, that is, the Eating Disorder Examination. RESULTS: Receiver-operating characteristic analyses showed that, regardless of treatment, symptom reduction at session six predicted remission at posttreatment (AUC = 0.814 (p < .001)) and 6-month follow-up (AUC = 0.811 (p < .001)). CONCLUSION: Results suggest that adolescents with BN who do not show early reductions in bulimic symptoms are unlikely to remit at posttreatment or follow-up. (c) 2008 by Wiley Periodicals, Inc.
RCT Entities:
OBJECTIVE: The purpose of this study was to determine if early response predicted remission at the end of a controlled trial. METHOD: Eighty adolescents with bulimia nervosa participated in an RCT comparing family-based treatment and individual supportive psychotherapy. Response to treatment was assessed via self-report of bingeing and purging. Remission was defined as abstinence from bingeing and purging for the last 28 days and measured by investigator-based interview, that is, the Eating Disorder Examination. RESULTS: Receiver-operating characteristic analyses showed that, regardless of treatment, symptom reduction at session six predicted remission at posttreatment (AUC = 0.814 (p < .001)) and 6-month follow-up (AUC = 0.811 (p < .001)). CONCLUSION: Results suggest that adolescents with BN who do not show early reductions in bulimic symptoms are unlikely to remit at posttreatment or follow-up. (c) 2008 by Wiley Periodicals, Inc.
Authors: Christopher G Fairburn; W Stewart Agras; B Timothy Walsh; G Terence Wilson; Eric Stice Journal: Am J Psychiatry Date: 2004-12 Impact factor: 18.112
Authors: Lynn L Debar; G Terence Wilson; Bobbi Jo Yarborough; Beryl Burns; Barbara Oyler; Tom Hildebrandt; Gregory N Clarke; John Dickerson; Ruth H Striegel Journal: Cogn Behav Pract Date: 2013-05-01