Literature DB >> 18569170

Mechanism and treatment of sulfide-induced coma: a rat model.

A F Almeida1, P N Nation, T L Guidotti.   

Abstract

Sodium hydrosulfide and dimethylsulfide duplicate the effects of hydrogen sulfide in causing coma in Sprague-Dawley rats and are additive for lethality. Nitrite, pyruvate and dithiothreitol had no significant effect on coma or lethality but bicarbonate with and without glucose reduced duration of coma. This finding suggests an antidotal treatment.

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Year:  2008        PMID： 18569170     DOI： 10.1080/10915810802210166

Source DB:  PubMed          Journal:  Int J Toxicol        ISSN： 1091-5818            Impact factor:   2.032


  6 in total

1.  H2S induced coma and cardiogenic shock in the rat: Effects of phenothiazinium chromophores.

Authors:  Takashi Sonobe; Philippe Haouzi
Journal:  Clin Toxicol (Phila)       Date:  2015-05-12       Impact factor: 4.467

2.  H2S concentrations in the arterial blood during H2S administration in relation to its toxicity and effects on breathing.

Authors:  Candice M Klingerman; Neil Trushin; Bogdan Prokopczyk; Philippe Haouzi
Journal:  Am J Physiol Regul Integr Comp Physiol       Date:  2013-07-31       Impact factor: 3.619

3.  Concentration-time extrapolation of short-term inhalation exposure levels: dimethyl sulfide, a case study using a chemical-specific toxic load exponent.

Authors:  Eugene Demchuk; Shannon L Ball; San L Le; Andrew J Prussia
Journal:  Inhal Toxicol       Date:  2019-01-02       Impact factor: 2.724

4.  In vivo interactions between cobalt or ferric compounds and the pools of sulphide in the blood during and after H2S poisoning.

Authors:  Philippe Haouzi; Takashi Sonobe; Nicole Torsell-Tubbs; Bogdan Prokopczyk; Bruno Chenuel; Candice M Klingerman
Journal:  Toxicol Sci       Date:  2014-07-11       Impact factor: 4.849

5.  Methylene Blue Administration During and After Life-Threatening Intoxication by Hydrogen Sulfide: Efficacy Studies in Adult Sheep and Mechanisms of Action.

Authors:  Philippe Haouzi; Nicole Tubbs; Joseph Cheung; Annick Judenherc-Haouzi
Journal:  Toxicol Sci       Date:  2019-04-01       Impact factor: 4.849

6.  Immediate and Long-Term Outcome of Acute H2S Intoxication Induced Coma in Unanesthetized Rats: Effects of Methylene Blue.

Authors:  Takashi Sonobe; Bruno Chenuel; Timothy K Cooper; Philippe Haouzi
Journal:  PLoS One       Date:  2015-06-26       Impact factor: 3.240
  6 in total

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