BACKGROUND: Increased arterial stiffness is a marker of cardiovascular damage, even in the absence of clinically apparent disease. It is likely to become an important clinical tool in cardiovascular risk assessment. AIMS AND METHODS: We studied a group of healthy subjects and measured their arterial stiffness by digital photoplethysmography. We aimed to obtain a range of arterial stiffness values, and investigated the influence of age, gender, race, body mass index, fasting lipids and haemodynamic factors. RESULTS: One hundred and fifty-two healthy subjects, aged between 18 and 67 years, on no medications and with no significant medical illnesses were recruited. The population was predominantly Caucasian (n = 112). Two measures of arterial stiffness were obtained: stiffness index (SI), a measure of large arterial stiffness, and reflection index (RI), a measure of small to medium-sized arterial stiffness. SI and RI were significantly correlated with age, total cholesterol, low-density lipoprotein-cholesterol, heart rate (HR), systolic blood pressure (SBP) and diastolic blood pressure (DBP). Race was a significant independent predictor of SI. CONCLUSION: Digital photoplethysmography is a portable, operator-independent, reproducible and simple method of measuring arterial stiffness. Ranges of normality of arterial stiffness will depend on the individual's age, race, lipid levels, HR and blood pressure.
BACKGROUND: Increased arterial stiffness is a marker of cardiovascular damage, even in the absence of clinically apparent disease. It is likely to become an important clinical tool in cardiovascular risk assessment. AIMS AND METHODS: We studied a group of healthy subjects and measured their arterial stiffness by digital photoplethysmography. We aimed to obtain a range of arterial stiffness values, and investigated the influence of age, gender, race, body mass index, fasting lipids and haemodynamic factors. RESULTS: One hundred and fifty-two healthy subjects, aged between 18 and 67 years, on no medications and with no significant medical illnesses were recruited. The population was predominantly Caucasian (n = 112). Two measures of arterial stiffness were obtained: stiffness index (SI), a measure of large arterial stiffness, and reflection index (RI), a measure of small to medium-sized arterial stiffness. SI and RI were significantly correlated with age, total cholesterol, low-density lipoprotein-cholesterol, heart rate (HR), systolic blood pressure (SBP) and diastolic blood pressure (DBP). Race was a significant independent predictor of SI. CONCLUSION: Digital photoplethysmography is a portable, operator-independent, reproducible and simple method of measuring arterial stiffness. Ranges of normality of arterial stiffness will depend on the individual's age, race, lipid levels, HR and blood pressure.
Authors: Md Rizman Md Lazin Md Lazim; Amilia Aminuddin; Kalaivani Chellappan; Azizah Ugusman; Adila A Hamid; Wan Amir Nizam Wan Ahmad; Mohd Shawal Faizal Mohamad Journal: Int J Environ Res Public Health Date: 2020-04-10 Impact factor: 3.390
Authors: Peter H Charlton; Birutė Paliakaitė; Kristjan Pilt; Martin Bachler; Serena Zanelli; Dániel Kulin; John Allen; Magid Hallab; Elisabetta Bianchini; Christopher C Mayer; Dimitrios Terentes-Printzios; Verena Dittrich; Bernhard Hametner; Dave Veerasingam; Dejan Žikić; Vaidotas Marozas Journal: Am J Physiol Heart Circ Physiol Date: 2021-12-24 Impact factor: 4.733