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Literature DB >> 18568400

Concise synthesis of a heptasaccharide antigen found in the cell-wall lipopolysaccharide of Mycobacterium gordonae strain 990.

Abstract

A straight forward synthesis of a heptasaccharide part of the cell-wall lipopolysaccharide of Mycobacterium gordonae strain 990, known to have antigenicity, has been achieved in excellent yield. Judicious choice of protecting groups in the intermediates played a significant role throughout the synthesis. Most of the intermediate steps furnished satisfactory yield.

Entities: Chemical Species

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Year: 2008 PMID： 18568400 DOI： 10.1007/s10719-008-9142-8

Source DB: PubMed Journal: Glycoconj J ISSN： 0282-0080 Impact factor: 2.916

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References

20 in total

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Authors: W T Jansen; S Hogenboom; M J Thijssen; J P Kamerling; J F Vliegenthart; J Verhoef; H Snippe; A F Verheul
Journal: Infect Immun Date: 2001-02 Impact factor: 3.441

Review 2. Progress towards development of a cholera subunit vaccine.

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Authors: René Roy
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5. Direct one-pot conversion of acylated carbohydrates into their alkylated derivatives under heterogeneous reaction conditions using solid NaOH and a phase transfer catalyst.

Authors: Soni Kamlesh Madhusudan; Geetanjali Agnihotri; Devendra S Negi; Anup Kumar Misra
Journal: Carbohydr Res Date: 2005-05-23 Impact factor: 2.104

10. Synthetic fragments of Vibrio cholerae O1 Inaba O-specific polysaccharide bound to a protein carrier are immunogenic in mice but do not induce protective antibodies.

Authors: Michael D Meeks; Rina Saksena; Xingquan Ma; Terri K Wade; Ronald K Taylor; Pavol Kovác; William F Wade
Journal: Infect Immun Date: 2004-07 Impact factor: 3.441

Concise synthesis of a heptasaccharide antigen found in the cell-wall lipopolysaccharide of Mycobacterium gordonae strain 990.

1. Synthetic 6B di-, tri-, and tetrasaccharide-protein conjugates contain pneumococcal type 6A and 6B common and 6B-specific epitopes that elicit protective antibodies in mice.

Review 2. Progress towards development of a cholera subunit vaccine.

3. New trends in carbohydrate-based vaccines.

Review 4. Disseminated infection with Mycobacterium gordonae: report of a case and critical review of the literature.

5. Direct one-pot conversion of acylated carbohydrates into their alkylated derivatives under heterogeneous reaction conditions using solid NaOH and a phase transfer catalyst.

6. A pseudoepidemic due to atypical mycobacteria in a hospital water supply.

Review 7. Functional aspects of the Leishmania donovani lipophosphoglycan during macrophage infection.

8. Preparation of a semisynthetic vaccine to Streptococcus pneumoniae type 3.

9. Synthetic GPI as a candidate anti-toxic vaccine in a model of malaria.

10. Synthetic fragments of Vibrio cholerae O1 Inaba O-specific polysaccharide bound to a protein carrier are immunogenic in mice but do not induce protective antibodies.