Literature DB >> 18567789

Purine salvage pathways in the intraerythrocytic malaria parasite Plasmodium falciparum.

Megan J Downie1, Kiaran Kirk, Choukri Ben Mamoun.   

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Year:  2008        PMID： 18567789      PMCID： PMC2519781          DOI： 10.1128/EC.00159-08

Source DB:  PubMed          Journal:  Eukaryot Cell        ISSN： 1535-9786


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  69 in total

Review 1.  Immucillins as antibiotics for T-cell proliferation and malaria.

Authors:  Vern L Schramm
Journal:  Nucleosides Nucleotides Nucleic Acids       Date:  2004-10       Impact factor: 1.381

Review 2.  Purine and pyrimidine transport in pathogenic protozoa: from biology to therapy.

Authors:  Harry P de Koning; Daniel J Bridges; Richard J S Burchmore
Journal:  FEMS Microbiol Rev       Date:  2005-07-01       Impact factor: 16.408

3.  The Plasmodium falciparum sexual development transcriptome: a microarray analysis using ontology-based pattern identification.

Authors:  Jason A Young; Quinton L Fivelman; Peter L Blair; Patricia de la Vega; Karine G Le Roch; Yingyao Zhou; Daniel J Carucci; David A Baker; Elizabeth A Winzeler
Journal:  Mol Biochem Parasitol       Date:  2005-09       Impact factor: 1.759

4.  A proof-of-principle pharmacokinetic, pharmacodynamic, and clinical study with purine nucleoside phosphorylase inhibitor immucillin-H (BCX-1777, forodesine).

Authors:  Varsha Gandhi; John M Kilpatrick; William Plunkett; Mary Ayres; Leigh Harman; Min Du; Shanta Bantia; Jan Davisson; William G Wierda; Stefan Faderl; Hagop Kantarjian; Deborah Thomas
Journal:  Blood       Date:  2005-08-30       Impact factor: 22.113

5.  Purine nucleobase transport in the intraerythrocytic malaria parasite.

Authors:  Megan J Downie; Kevin J Saliba; Stefan Bröer; Susan M Howitt; Kiaran Kirk
Journal:  Int J Parasitol       Date:  2007-07-25       Impact factor: 3.981

6.  Synthesis of 5'-methylthio coformycins: specific inhibitors for malarial adenosine deaminase.

Authors:  Peter C Tyler; Erika A Taylor; Richard F G Fröhlich; Vern L Schramm
Journal:  J Am Chem Soc       Date:  2007-05-08       Impact factor: 15.419

7.  A comprehensive model of purine uptake by the malaria parasite Plasmodium falciparum: identification of four purine transport activities in intraerythrocytic parasites.

Authors:  Neils B Quashie; Dominique Dorin-Semblat; Patrick G Bray; Giancarlo A Biagini; Christian Doerig; Lisa C Ranford-Cartwright; Harry P De Koning
Journal:  Biochem J       Date:  2008-04-15       Impact factor: 3.857

Review 8.  Purine and pyrimidine metabolism in Leishmania.

Authors:  Nicola S Carter; Phillip Yates; Cassandra S Arendt; Jan M Boitz; Buddy Ullman
Journal:  Adv Exp Med Biol       Date:  2008       Impact factor: 2.622

9.  Genetic evidence for the essential role of PfNT1 in the transport and utilization of xanthine, guanine, guanosine and adenine by Plasmodium falciparum.

Authors:  Kamal El Bissati; Megan J Downie; Seong-Kyoun Kim; Michael Horowitz; Nicola Carter; Buddy Ullman; Choukri Ben Mamoun
Journal:  Mol Biochem Parasitol       Date:  2008-07-03       Impact factor: 1.759

10.  Kinetic and biochemical characterization of Plasmodium falciparum GMP synthetase.

Authors:  Javaid Yousuf Bhat; Brahmanaspati Ganapathi Shastri; Hemalatha Balaram
Journal:  Biochem J       Date:  2008-01-01       Impact factor: 3.857
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  39 in total

1.  Transmembrane segment 11 appears to line the purine permeation pathway of the Plasmodium falciparum equilibrative nucleoside transporter 1 (PfENT1).

Authors:  Paul M Riegelhaupt; I J Frame; Myles H Akabas
Journal:  J Biol Chem       Date:  2010-03-24       Impact factor: 5.157

2.  Host-parasite interactions revealed by Plasmodium falciparum metabolomics.

Authors:  Kellen L Olszewski; Joanne M Morrisey; Daniel Wilinski; James M Burns; Akhil B Vaidya; Joshua D Rabinowitz; Manuel Llinás
Journal:  Cell Host Microbe       Date:  2009-02-19       Impact factor: 21.023

3.  UV-triggered affinity capture identifies interactions between the Plasmodium falciparum multidrug resistance protein 1 (PfMDR1) and antimalarial agents in live parasitized cells.

Authors:  Ralf Brunner; Caroline L Ng; Hamed Aissaoui; Myles H Akabas; Christoph Boss; Reto Brun; Paul S Callaghan; Olivier Corminboeuf; David A Fidock; Ithiel J Frame; Bibia Heidmann; Amélie Le Bihan; Paul Jenö; Corinna Mattheis; Suzette Moes; Ingrid B Müller; Michelle Paguio; Paul D Roepe; Romain Siegrist; Till Voss; Richard W D Welford; Sergio Wittlin; Christoph Binkert
Journal:  J Biol Chem       Date:  2013-06-10       Impact factor: 5.157

4.  Fragment-based drug discovery using a multidomain, parallel MD-MM/PBSA screening protocol.

Authors:  Tian Zhu; Hyun Lee; Hao Lei; Christopher Jones; Kavankumar Patel; Michael E Johnson; Kirk E Hevener
Journal:  J Chem Inf Model       Date:  2013-03-14       Impact factor: 4.956

5.  Metabolic fate of fumarate, a side product of the purine salvage pathway in the intraerythrocytic stages of Plasmodium falciparum.

Authors:  Vinay Bulusu; Vijay Jayaraman; Hemalatha Balaram
Journal:  J Biol Chem       Date:  2011-01-05       Impact factor: 5.157

6.  Metabolic modeling helps interpret transcriptomic changes during malaria.

Authors:  Yan Tang; Anuj Gupta; Swetha Garimalla; Mary R Galinski; Mark P Styczynski; Luis L Fonseca; Eberhard O Voit
Journal:  Biochim Biophys Acta Mol Basis Dis       Date:  2017-10-22       Impact factor: 5.187

7.  Identification via a Parallel Hit Progression Strategy of Improved Small Molecule Inhibitors of the Malaria Purine Uptake Transporter that Inhibit Plasmodium falciparum Parasite Proliferation.

Authors:  Yvett Sosa; Roman Deniskin; I J Frame; Matthew S Steiginga; Deepak Bandyopadhyay; Todd L Graybill; Lorena A Kallal; Michael T Ouellette; Andrew J Pope; Katherine L Widdowson; Robert J Young; Myles H Akabas
Journal:  ACS Infect Dis       Date:  2019-08-14       Impact factor: 5.084

8.  Plasmodium falciparum purine nucleoside phosphorylase is critical for viability of malaria parasites.

Authors:  Dennis C Madrid; Li-Min Ting; Karena L Waller; Vern L Schramm; Kami Kim
Journal:  J Biol Chem       Date:  2008-10-28       Impact factor: 5.157

9.  Branched tricarboxylic acid metabolism in Plasmodium falciparum.

Authors:  Kellen L Olszewski; Michael W Mather; Joanne M Morrisey; Benjamin A Garcia; Akhil B Vaidya; Joshua D Rabinowitz; Manuel Llinás
Journal:  Nature       Date:  2010-08-05       Impact factor: 49.962

10.  Transport of purines and purine salvage pathway inhibitors by the Plasmodium falciparum equilibrative nucleoside transporter PfENT1.

Authors:  Paul M Riegelhaupt; María B Cassera; Richard F G Fröhlich; Keith Z Hazleton; Jonathan J Hefter; Vern L Schramm; Myles H Akabas
Journal:  Mol Biochem Parasitol       Date:  2009-10-08       Impact factor: 1.759
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