| Literature DB >> 18567053 |
Teruhiko Nitoda1, Takahiko Isobe, Isao Kubo.
Abstract
Pedalitin isolated from the aerial part of Rabdosia japonica (Labiatae), exhibited cytotoxicity against the murine B16-F10 melanoma cell line with an IC(50) of 30 microm (9.5 microg/mL). As the cells were cultured with this flavone, melanin production was not suppressed, but rather enhanced. Quercetin isolated from the same source exhibited similar activities, but rutin showed neither activity.Entities:
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Year: 2008 PMID： 18567053 DOI： 10.1002/ptr.2373
Source DB: PubMed Journal: Phytother Res ISSN： 0951-418X Impact factor: 5.878