Literature DB >> 18565152

Effects of mode of oral iron administration on serum ferritin and haemoglobin in infants.

Magnus Domellöf1, Torbjörn Lind, Bo Lönnerdal, Lars Ake Persson, Kathryn G Dewey, Olle Hernell.   

Abstract

AIM: To investigate effects of iron-fortified foods (FFs) and medicinal iron drops (MD) on iron status in infants.
METHODS: Data from one MD and one FF study were compared. Infants were divided into groups depending on the predominant source and amount of dietary iron during 6-9 months of age: MD: Medicinal iron drops (1 mg/kg/day). FF: iron intake >1.3 mg/kg/day, predominantly from FF and no iron supplements. Low iron (LI) group: iron intake <1.3 mg/kg/day and no iron supplements.
RESULTS: Mean iron intake did not differ between MD (n = 30) and FF (n = 35) groups but was lower in the LI (n = 232) group. The FF group had significantly higher mean Hb at 9 months compared to the MD and LI groups (120 vs. 115 g/L and 120 vs. 116 g/L, respectively, p < or = 0.005). The MD group had significantly higher mean SF at 9 months compared to the FF and the LI groups (46 vs. 23 microg/L and 46 vs. 26 microg/L, respectively, p < 0.001).
CONCLUSIONS: Our results suggest that, in healthy, term, nonanaemic 6-9-month-old infants, iron given as medicinal iron drops is primarily deposited into iron stores while iron given as iron-fortified foods is primarily utilized for Hb synthesis.

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Year:  2008        PMID: 18565152     DOI: 10.1111/j.1651-2227.2008.00899.x

Source DB:  PubMed          Journal:  Acta Paediatr        ISSN: 0803-5253            Impact factor:   2.299


  5 in total

Review 1.  Iron deficiency anemia from diagnosis to treatment in children.

Authors:  Nihal Özdemir
Journal:  Turk Pediatri Ars       Date:  2015-03-01

2.  Effect of iron supplementation during lactation on maternal iron status and oxidative stress: A randomized controlled trial.

Authors:  Josh M Jorgensen; Zhenyu Yang; Bo Lönnerdal; Caroline J Chantry; Kathryn G Dewey
Journal:  Matern Child Nutr       Date:  2016-11-29       Impact factor: 3.092

Review 3.  Developmental Physiology of Iron Absorption, Homeostasis, and Metabolism in the Healthy Term Infant.

Authors:  Bo Lönnerdal; Michael K Georgieff; Olle Hernell
Journal:  J Pediatr       Date:  2015-10       Impact factor: 4.406

Review 4.  Development of iron homeostasis in infants and young children.

Authors:  Bo Lönnerdal
Journal:  Am J Clin Nutr       Date:  2017-10-25       Impact factor: 7.045

5.  Does the fortified milk with high iron dose improve the neurodevelopment of healthy infants? Randomized controlled trial.

Authors:  Lucía Iglesias Vázquez; Josefa Canals; Núria Voltas; Cristina Jardí; Carmen Hernández; Cristina Bedmar; Joaquín Escribano; Núria Aranda; Rosa Jiménez; Josep Maria Barroso; Blanca Ribot; Victoria Arija
Journal:  BMC Pediatr       Date:  2019-09-05       Impact factor: 2.125

  5 in total

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