| Literature DB >> 18564680 |
Rungtip Chuanchuen1, Chailai Koowatananukul, Sirintip Khemtong.
Abstract
The unusual 3' conserved sequence region of class 1 integrons was characterized in seven Salmonella isolates from swine and poultry. Three types of gene cassette arrays, aadA2-cmlA1-aadA1, sat-psp-aadA2-cm1A1-aadA1 and drfA12-orf-aadA2-cmlA1-aadA1, were found to be linked to a genetic organization qacH-IS440-sul3. All class 1 integrons were located on a conjugative plasmid that could be transferred to Escherichia coli. The results support the notion that the use of an antibiotic can select for resistance not only to that specific agent, but also to other unrelated antimicrobials including those that are no longer approved for use in food animal production.Entities:
Mesh:
Year: 2008 PMID: 18564680
Source DB: PubMed Journal: Southeast Asian J Trop Med Public Health ISSN: 0125-1562 Impact factor: 0.267