[Colitis cystica profunda].

Colitis cystica profunda is a rare benign disease, characterized by the presence of mucin-filled cysts in the submucosa layer of colon, which forms polypoid lesions. The most habitual type of clinical presentation is localized, at distal colon or in the rectum, and more rarely appears like a diffuse afectation of colon. We present a case of colitis cystica profunda with diffuse afectation of whole colon, which definitive diagnosis was for the histological finds of the endoscopy macrobiopsys realized to colon's polypoid lesions.