Literature DB >> 18563674

[Lung protective ventilation - protective effect of adequate supported spontaneous breathing].

Christian Putensen1, Thomas Muders, Stefan Kreyer, Hermann Wrigge.   

Abstract

Based on available data, it can be suggested that spontaneous breathing during ventilator support has not to be suppressed even in patients with severe pulmonary dysfunction if no contraindications are present. Experimental data do not support the contention that spontaneous breathing aggravates ventilator-induced lung injury. During spontaneous breathing increase in PTP is maximal in the depended lung areas in adjunct to the diaphragm and causes recruitment of initially atelectatic lung areas thereby avoiding cyclic alveolar collapse and reopening. This should result in a lung protective effect of adequate supported spontaneous breathing. Clinical data supported this belief demonstrating improvement in pulmonary gas exchange, systemic blood flow, and oxygen supply to the tissue and a decrease in days on ventilator support and duration of stay in the intensive care unit.

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Year:  2008        PMID: 18563674     DOI: 10.1055/s-2008-1081393

Source DB:  PubMed          Journal:  Anasthesiol Intensivmed Notfallmed Schmerzther        ISSN: 0939-2661            Impact factor:   0.698


  2 in total

Review 1.  [Lung protective ventilation in ARDS].

Authors:  I Biener; M Czaplik; J Bickenbach; R Rossaint
Journal:  Med Klin Intensivmed Notfmed       Date:  2012-08-22       Impact factor: 0.840

2.  Lower tidal volume strategy (≈3 ml/kg) combined with extracorporeal CO2 removal versus 'conventional' protective ventilation (6 ml/kg) in severe ARDS: the prospective randomized Xtravent-study.

Authors:  Thomas Bein; Steffen Weber-Carstens; Anton Goldmann; Thomas Müller; Thomas Staudinger; Jörg Brederlau; Ralf Muellenbach; Rolf Dembinski; Bernhard M Graf; Marlene Wewalka; Alois Philipp; Klaus-Dieter Wernecke; Matthias Lubnow; Arthur S Slutsky
Journal:  Intensive Care Med       Date:  2013-01-10       Impact factor: 17.440

  2 in total

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