INTRODUCTION: Recent research has suggested a possible link between toxoplasmic agents and schizophrenia. We aimed to assess this by measuring Toxoplasma gondii-associated antibodies in schizophrenia patients and controls METHODS: We used a commercially available enzyme-linked immunosorbent assay (ELISA) kit to measure the level of immunoglobulin G (IgG) and IgM antibodies in serum samples from schizophrenia patients (n=40) and from a group of non-schizophrenic control subjects (n=37) RESULTS: Among schizophrenic patients, 16 (40%) showed IgG seropositivity and two (5%) showed IgM seropositivity. Among the control group, five (13.5%) were found have IgG seropositivity and one (2.7%) showed IgM seropositivity. In our study we found that IgG T gondii antibodies were significantly higher in schizophrenia patients compared with controls CONCLUSIONS: This study supports the theory that toxoplasmic agents may have a role in the aetiology of schizophrenia.
INTRODUCTION: Recent research has suggested a possible link between toxoplasmic agents and schizophrenia. We aimed to assess this by measuring Toxoplasma gondii-associated antibodies in schizophreniapatients and controls METHODS: We used a commercially available enzyme-linked immunosorbent assay (ELISA) kit to measure the level of immunoglobulin G (IgG) and IgM antibodies in serum samples from schizophreniapatients (n=40) and from a group of non-schizophrenic control subjects (n=37) RESULTS: Among schizophrenicpatients, 16 (40%) showed IgG seropositivity and two (5%) showed IgM seropositivity. Among the control group, five (13.5%) were found have IgG seropositivity and one (2.7%) showed IgM seropositivity. In our study we found that IgG T gondii antibodies were significantly higher in schizophreniapatients compared with controls CONCLUSIONS: This study supports the theory that toxoplasmic agents may have a role in the aetiology of schizophrenia.
Authors: José Gutiérrez-Fernández; Juan de Dios Luna Del Castillo; Sara Mañanes-González; José Antonio Carrillo-Ávila; Blanca Gutiérrez; Jorge A Cervilla; Antonio Sorlózano-Puerto Journal: Neuropsychiatr Dis Treat Date: 2015-03-27 Impact factor: 2.570
Authors: Ainsah Omar; Osman Che Bakar; Nor Fatini Adam; Hakim Osman; Arina Osman; Ahmad Hatim Suleiman; Mohd Rizal Abdul Manaf; Mohd Ikhsan Selamat Journal: Korean J Parasitol Date: 2015-02-27 Impact factor: 1.341