| Literature DB >> 18563248 |
Rujikan Nasanit1, Parvez Iqbal, Mahmoud Soliman, Neil Spencer, Stephanie Allen, Martyn C Davies, Simon S Briggs, Leonard W Seymour, Jon A Preece, Cameron Alexander.
Abstract
Variation in amino acid sequences on a disulfide-linked polypeptide backbone generates differing pK(a) vectors for DNA delivery, which release nucleic acids under reducing conditions and transfect cells with greater efficacy than non-reducible or non-variable pK(a) analogues.Entities:
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Year: 2008 PMID： 18563248 DOI： 10.1039/b803262a
Source DB: PubMed Journal: Mol Biosyst ISSN： 1742-2051