OBJECTIVE: The purpose of this study was to evaluate the MRI features of the "MR corner sign" and to determine its diagnostic usefulness in ankylosing spondylitis. We reviewed the spinal MR images of 52 patients with ankylosing spondylitis and compared these images with those of 52 age- and sex-matched control subjects. CONCLUSION: The MR corner sign was defined as a triangular and sharply marginated corner abnormality in a vertebral body unassociated with osteophytes or Schmorl's node. MR corner lesions were significantly more common in the ankylosing spondylitis group than in the control group (Fisher's exact test, p < 0.001). The sensitivity, specificity, and positive and negative predictive values of the MR corner sign were 44%, 96%, 92%, and 63%, respectively. The most frequent feature of signal intensity was a Modic type II change (77%). In patients with ankylosing spondylitis, the MR corner sign was fre quently seen at the thoracolumbar junction, whereas degenerative corner lesions were commonly seen in the lower lumbar spine. When the MR corner sign is detected on spinal MR images in daily practice, it should not be overlooked because it suggests the possibility of ankylosing spondylitis, which should then be further evaluated.
OBJECTIVE: The purpose of this study was to evaluate the MRI features of the "MR corner sign" and to determine its diagnostic usefulness in ankylosing spondylitis. We reviewed the spinal MR images of 52 patients with ankylosing spondylitis and compared these images with those of 52 age- and sex-matched control subjects. CONCLUSION: The MR corner sign was defined as a triangular and sharply marginated corner abnormality in a vertebral body unassociated with osteophytes or Schmorl's node. MR corner lesions were significantly more common in the ankylosing spondylitis group than in the control group (Fisher's exact test, p < 0.001). The sensitivity, specificity, and positive and negative predictive values of the MR corner sign were 44%, 96%, 92%, and 63%, respectively. The most frequent feature of signal intensity was a Modic type II change (77%). In patients with ankylosing spondylitis, the MR corner sign was fre quently seen at the thoracolumbar junction, whereas degenerative corner lesions were commonly seen in the lower lumbar spine. When the MR corner sign is detected on spinal MR images in daily practice, it should not be overlooked because it suggests the possibility of ankylosing spondylitis, which should then be further evaluated.
Authors: Alexis Jones; Timothy J P Bray; Peter Mandl; Margaret A Hall-Craggs; Helena Marzo-Ortega; Pedro M Machado Journal: Rheumatology (Oxford) Date: 2019-11-01 Impact factor: 7.580
Authors: I-H Song; K G Hermann; H Haibel; C E Althoff; D Poddubnyy; J Listing; A Weiss; B Freundlich; M Rudwaleit; J Sieper Journal: Ann Rheum Dis Date: 2011-05-08 Impact factor: 19.103
Authors: Susanne Juhl Pedersen; Zheng Zhao; Robert G W Lambert; Stephanie Wichuk; Mikkel Østergaard; Ulrich Weber; Walter P Maksymowych Journal: Arthritis Res Ther Date: 2013 Impact factor: 5.156
Authors: Mariagrazia Lorenzin; Augusta Ortolan; Mara Felicetti; Stefania Vio; Marta Favero; Pamela Polito; Carmelo Lacognata; Vanna Scapin; Andrea Doria; Roberta Ramonda Journal: Front Immunol Date: 2020-05-15 Impact factor: 7.561