Literature DB >> 18562652

The direction of linkage disequilibrium: a new measure based on the ancestral-derived status of segregating alleles.

K Ryo Takahasi1, Hideki Innan.   

Abstract

A new measure of directional linkage disequilibrium is developed for detecting epistatic selection on interacting genes. Simulations show that by orienting the direction of linkage disequilibrium on the basis of the ancestral-derived status of alleles, the new measure indeed improves the power to detect a positive fitness interaction between two new mutations.

Mesh：

Year:  2008        PMID： 18562652      PMCID： PMC2475762          DOI： 10.1534/genetics.107.085654

Source DB:  PubMed          Journal:  Genetics        ISSN： 0016-6731            Impact factor:   4.562


  8 in total

1.  Selection intensity against deleterious mutations in RNA secondary structures and rate of compensatory nucleotide substitutions.

Authors:  H Innan; W Stephan
Journal:  Genetics       Date:  2001-09       Impact factor: 4.562

2.  Functional coadaptation between cytochrome c and cytochrome c oxidase within allopatric populations of a marine copepod.

Authors:  Paul D Rawson; Ronald S Burton
Journal:  Proc Natl Acad Sci U S A       Date:  2002-09-23       Impact factor: 11.205

3.  Evolution of coadaptation in a two-locus epistatic system.

Authors:  K Ryo Takahasi; Fumio Tajima
Journal:  Evolution       Date:  2005-11       Impact factor: 3.694

4.  The Interaction of Selection and Linkage. I. General Considerations; Heterotic Models.

Authors:  R C Lewontin
Journal:  Genetics       Date:  1964-01       Impact factor: 4.562

5.  Linkage disequilibrium in finite populations.

Authors:  W G Hill; A Robertson
Journal:  Theor Appl Genet       Date:  1968-06       Impact factor: 5.699

6.  The direction of linkage disequilibrium.

Authors:  C H Langley; J F Crow
Journal:  Genetics       Date:  1974-11       Impact factor: 4.562

7.  Linkage disequilibrium in natural populations of Drosophila melanogaster.

Authors:  C H Langley; Y N Tobari; K I Kojima
Journal:  Genetics       Date:  1974-11       Impact factor: 4.562

8.  Epistatic interaction between Arabidopsis FRI and FLC flowering time genes generates a latitudinal cline in a life history trait.

Authors:  Ana L Caicedo; John R Stinchcombe; Kenneth M Olsen; Johanna Schmitt; Michael D Purugganan
Journal:  Proc Natl Acad Sci U S A       Date:  2004-10-25       Impact factor: 11.205
  8 in total
  3 in total

1.  Fine-Scale Haplotype Structure Reveals Strong Signatures of Positive Selection in a Recombining Bacterial Pathogen.

Authors:  Brian Arnold; Mashaal Sohail; Crista Wadsworth; Jukka Corander; William P Hanage; Shamil Sunyaev; Yonatan H Grad
Journal:  Mol Biol Evol       Date:  2020-02-01       Impact factor: 16.240

2.  A linkage disequilibrium-based statistical test for Genome-Wide Epistatic Selection Scans in structured populations.

Authors:  Léa Boyrie; Corentin Moreau; Florian Frugier; Christophe Jacquet; Maxime Bonhomme
Journal:  Heredity (Edinb)       Date:  2020-07-30       Impact factor: 3.821

3.  Correlated evolution of nearby residues in Drosophilid proteins.

Authors:  Benjamin Callahan; Richard A Neher; Doris Bachtrog; Peter Andolfatto; Boris I Shraiman
Journal:  PLoS Genet       Date:  2011-02-24       Impact factor: 5.917
  3 in total

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