Literature DB >> 185626

Opiate receptor: autoradiographic localization in rat brain.

C B Pert, M J Kuhar, S H Snyder.   

Abstract

Opiate receptor sites in rat brain can be labeled in vivo by [3H]diprenorphine, a potent opiate antagoinst. Using techniques to minimize diffusion in fresh, frozen, unfixed brain, we have localized [3H]diprenorphine by autoradiography to visualize the distribution of opiate receptors. Silver grains indicative of the binding of labeled [3H]diprenorphine are discretely localized in numerous areas of the brain with very high densities in the locus coeruleus, the substantia gelatinosa of the spinal cord, and in clusters within the caudate-putamen, amygdala, and parts of the periventricular gray matter.

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Year:  1976        PMID： 185626      PMCID： PMC431193          DOI： 10.1073/pnas.73.10.3729

Source DB:  PubMed          Journal:  Proc Natl Acad Sci U S A        ISSN： 0027-8424            Impact factor:   11.205


  21 in total

1.  Search for an endogenous ligand for the opiate receptor.

Authors:  L Terenius; A Wahlström
Journal:  Acta Physiol Scand       Date:  1975-05

2.  Autoradiograhic localization of the opiate receptor in rat brain.

Authors:  C B Pert; M J Kuhar; S H Snyder
Journal:  Life Sci       Date:  1975-06-15       Impact factor: 5.037

3.  Light autoradiographic localisation of cholinergic muscarinic receptors in rat brain by specific binding of a potent antagonist.

Authors:  M J Kuhar; H I Yamamura
Journal:  Nature       Date:  1975-02-13       Impact factor: 49.962

4.  Role of gelatinous substance of spinal cord in conduction of pain.

Authors:  A A PEARSON
Journal:  AMA Arch Neurol Psychiatry       Date:  1952-10

5.  Sites of morphine induced analgesia in the primate brain: relation to pain pathways.

Authors:  A Pert; T Yaksh
Journal:  Brain Res       Date:  1974-11-08       Impact factor: 3.252

6.  Noradrenergic neurons: morphine inhibition of spontaneous activity.

Authors:  J Korf; B S Bunney; G K Aghajanian
Journal:  Eur J Pharmacol       Date:  1974-02       Impact factor: 4.432

7.  Regional distribution of opiate receptor binding in monkey and human brain.

Authors:  M J Kuhar; C B Pert; S H Snyder
Journal:  Nature       Date:  1973-10-26       Impact factor: 49.962

8.  Stereotaxic mapping of the monoamine pathways in the rat brain.

Authors:  U Ungerstedt
Journal:  Acta Physiol Scand Suppl       Date:  1971

9.  Morphine action at central nervous system sites in rat: analgesia or hyperalgesia depending on site and dose.

Authors:  Y F Jacquet; A Lajtha
Journal:  Science       Date:  1973-11-02       Impact factor: 47.728

10.  Morphine-like peptides in mammalian brain: isolation, structure elucidation, and interactions with the opiate receptor.

Authors:  R Simantov; S H Snyder
Journal:  Proc Natl Acad Sci U S A       Date:  1976-07       Impact factor: 11.205
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  88 in total

1.  Effects of intraseptal administration of cholinergic agents on morphine-induced behavior of cats.

Authors:  A A Megens; A R Cools
Journal:  Psychopharmacology (Berl)       Date:  1979-11       Impact factor: 4.530

2.  Histochemically distinct compartments in the striatum of human, monkeys, and cat demonstrated by acetylthiocholinesterase staining.

Authors:  A M Graybiel; C W Ragsdale
Journal:  Proc Natl Acad Sci U S A       Date:  1978-11       Impact factor: 11.205

3.  Subsets of Spiny Striosomal Striatal Neurons Revealed in the Gad1-GFP BAC Transgenic Mouse.

Authors:  Verginia C Cuzon Carlson; Brian N Mathur; Margaret I Davis; David M Lovinger
Journal:  Basal Ganglia       Date:  2011-11-01

4.  Methamphetamine-induced stereotypy correlates negatively with patch-enhanced prodynorphin and arc mRNA expression in the rat caudate putamen: the role of mu opioid receptor activation.

Authors:  Kristen A Horner; Erika S Noble; Yamiece E Gilbert
Journal:  Pharmacol Biochem Behav       Date:  2010-03-15       Impact factor: 3.533

5.  κ-Opioid receptors within the nucleus accumbens shell mediate pair bond maintenance.

Authors:  Shanna L Resendez; Morgan Kuhnmuench; Tarin Krzywosinski; Brandon J Aragona
Journal:  J Neurosci       Date:  2012-05-16       Impact factor: 6.167

6.  Octapeptides deduced from the neuropeptide receptor-like pattern of antigen T4 in brain potently inhibit human immunodeficiency virus receptor binding and T-cell infectivity.

Authors:  C B Pert; J M Hill; M R Ruff; R M Berman; W G Robey; L O Arthur; F W Ruscetti; W L Farrar
Journal:  Proc Natl Acad Sci U S A       Date:  1986-12       Impact factor: 11.205

7.  Role of central and peripheral opiate receptors in the effects of fentanyl on analgesia, ventilation and arterial blood-gas chemistry in conscious rats.

Authors:  Fraser Henderson; Walter J May; Ryan B Gruber; Joseph F Discala; Veljko Puskovic; Alex P Young; Santhosh M Baby; Stephen J Lewis
Journal:  Respir Physiol Neurobiol       Date:  2013-11-24       Impact factor: 1.931

Review 8.  Tactics for preclinical validation of receptor-binding radiotracers.

Authors:  Susan Z Lever; Kuo-Hsien Fan; John R Lever
Journal:  Nucl Med Biol       Date:  2016-09-03       Impact factor: 2.408

9.  Genetic-Based Dissection Unveils the Inputs and Outputs of Striatal Patch and Matrix Compartments.

Authors:  Jared B Smith; Jason R Klug; Danica L Ross; Christopher D Howard; Nick G Hollon; Vivian I Ko; Hilary Hoffman; Edward M Callaway; Charles R Gerfen; Xin Jin
Journal:  Neuron       Date:  2016-08-25       Impact factor: 17.173

10.  Visualization of opiate receptor upregulation by light microscopy autoradiography.

Authors:  A Tempel; E L Gardner; R S Zukin
Journal:  Proc Natl Acad Sci U S A       Date:  1984-06       Impact factor: 11.205
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