| Literature DB >> 18560362 |
Abstract
Vascular access failure is a major clinical problem for patients on hemodialysis, but therapeutic approaches aimed at improving arteriovenous fistula (AVF) dysfunction remain elusive. Using a murine AVF model, Juncos et al. demonstrate for the first time that the stress protein heme oxygenase-1 (HO-1) is induced in AVFs and that HO-1 is a critical determinant of AVF survival.Entities:
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Year: 2008 PMID: 18560362 PMCID: PMC2645071 DOI: 10.1038/ki.2008.127
Source DB: PubMed Journal: Kidney Int ISSN: 0085-2538 Impact factor: 10.612