OBJECTIVES: The use of antimicrobial prophylaxis against surgical site infection (SSI) is widespread in plastic surgery, while results from prospective randomised controlled trials in guiding antibiotic use are lacking. The purpose of this study was to identify the incidence and risk factors for SSI in plastic surgery, and to evaluate the appropriateness of prophylactic antibiotic prescribing habits in a tertiary university centre. METHODS: A retrospective chart review was conducted over a 6-month period. Co-morbidities, types of procedure, prophylactic antimicrobial administration, SSI rates, and clinical outcomes were evaluated. RESULTS: The incidence of SSI was 9.3% for 335 procedures. The cumulative incidence of SSI for breast surgery (n=80) was 16.3%, with a 78.8% prescription rate. For head and neck procedures (n=68), the incidence of SSI was 10.3%, with 80.9% of patients receiving antibiotic prophylaxis. For hand and upper limb procedures (n=170), 70.6% of patients received antimicrobial prophylaxis, with a 4.7% SSI incidence. According to category A prophylaxis guidelines published in the plastic surgery literature, over prescribing was identified in 27.5% of breast, 61.8% of head and neck, and 19.4% of hand and upper limb procedures. CONCLUSIONS: This is the first study evaluating appropriateness of antimicrobial prophylaxis use by plastic surgeons. Despite widespread use of prophylactic antibiotics, significant SSI rates were still present and frequently responsible for re-hospitalisations and re-interventions. The appropriateness of administration and indications for perioperative prophylactic antibiotic use must be evaluated.
OBJECTIVES: The use of antimicrobial prophylaxis against surgical site infection (SSI) is widespread in plastic surgery, while results from prospective randomised controlled trials in guiding antibiotic use are lacking. The purpose of this study was to identify the incidence and risk factors for SSI in plastic surgery, and to evaluate the appropriateness of prophylactic antibiotic prescribing habits in a tertiary university centre. METHODS: A retrospective chart review was conducted over a 6-month period. Co-morbidities, types of procedure, prophylactic antimicrobial administration, SSI rates, and clinical outcomes were evaluated. RESULTS: The incidence of SSI was 9.3% for 335 procedures. The cumulative incidence of SSI for breast surgery (n=80) was 16.3%, with a 78.8% prescription rate. For head and neck procedures (n=68), the incidence of SSI was 10.3%, with 80.9% of patients receiving antibiotic prophylaxis. For hand and upper limb procedures (n=170), 70.6% of patients received antimicrobial prophylaxis, with a 4.7% SSI incidence. According to category A prophylaxis guidelines published in the plastic surgery literature, over prescribing was identified in 27.5% of breast, 61.8% of head and neck, and 19.4% of hand and upper limb procedures. CONCLUSIONS: This is the first study evaluating appropriateness of antimicrobial prophylaxis use by plastic surgeons. Despite widespread use of prophylactic antibiotics, significant SSI rates were still present and frequently responsible for re-hospitalisations and re-interventions. The appropriateness of administration and indications for perioperative prophylactic antibiotic use must be evaluated.
Authors: Smeem Jaber; Crystal Rogers; Bruce Sunderland; Richard Parsons; Sarah MacKenzie; Jason Seet; Petra Czarniak Journal: Int J Clin Pharm Date: 2017-02-15
Authors: Amy C Degnim; Tanya L Hoskin; Rushin D Brahmbhatt; Anne Warren-Peled; Margie Loprinzi; Emily S Pavey; Judy C Boughey; Tina J Hieken; Steven Jacobson; Valerie Lemaine; James W Jakub; Chetan Irwin; Robert D Foster; Hani Sbitany; Michel Saint-Cyr; Erin Duralde; Sheri Ramaker; Robin Chin; Monica Sieg; Melissa Wildeman; Jeffrey S Scow; Robin Patel; Karla Ballman; Larry M Baddour; Laura J Esserman Journal: Ann Surg Oncol Date: 2014-08-06 Impact factor: 5.344
Authors: Femke M A P Claessen; Yvonne Braun; Wouter F van Leeuwen; George S Dyer; Michel P J van den Bekerom; David Ring Journal: Clin Orthop Relat Res Date: 2015-08-25 Impact factor: 4.176
Authors: Amy C Degnim; Jeffrey S Scow; Tanya L Hoskin; Joyce P Miller; Margie Loprinzi; Judy C Boughey; James W Jakub; Alyssa Throckmorton; Robin Patel; Larry M Baddour Journal: Ann Surg Date: 2013-08 Impact factor: 12.969