Literature DB >> 18556936

Intravitreal bevacizumab for myopic choroidal neovascularization.

Florian Rensch1, Ulrich H M Spandau, Frank Schlichtenbrede, Stefan von Baltz, Teodosio Libondi, Jost B Jonas, Urs Vossmerbaeumer.   

Abstract

BACKGROUND AND
OBJECTIVE: To evaluate the effect of intravitreal bevacizumab on visual acuity in patients with myopic choroidal neovascularization. PATIENTS AND METHODS: The retrospective case series study included 13 patients with myopic choroidal neovascularization who received three intravitreal injections of 1.5 mg of bevacizumab.
RESULTS: At 1, 3, and 6 months after the first injection, mean visual acuity improved significantly from 0.63 +/- 0.41 logarithm of the minimum angle of resolution units (LogMAR) to 0.39 +/- 0.22 (P< .001), 0.47 +/- 0.49 (P= .002), and 0.52 +/- 0.49 LogMAR (P = 0.009), respectively. The increase in visual acuity was correlated with a significant decrease in central retinal thickness (P = .003) as measured by optical coherence tomography. Mean intraocular pressure did not change significantly (P> .05) during follow-up.
CONCLUSION: Intravitreal injections of bevacizumab may be a therapeutic option for exudative myopic macular degeneration.

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Year:  2008        PMID: 18556936     DOI: 10.3928/15428877-20080501-14

Source DB:  PubMed          Journal:  Ophthalmic Surg Lasers Imaging        ISSN: 1542-8877


  3 in total

1.  Bevacizumab for choroidal neovascularization secondary to pathologic myopia: Is there a decline of the treatment efficacy after 2 years?

Authors:  Bogomil Voykov; Faik Gelisken; Werner Inhoffen; Michael Voelker; Karl Ulrich Bartz-Schmidt; Focke Ziemssen
Journal:  Graefes Arch Clin Exp Ophthalmol       Date:  2010-01-29       Impact factor: 3.117

2.  Treatment of myopic choroidal neovascularization with posterior sub-Tenon's bevacizumab injection (Avastin ®).

Authors:  I-Chia Liang; Yu-Ying Chang; Tong-Sheng Lee; Yi-Ru Lin; Kwan-Rong Liu
Journal:  Int Ophthalmol       Date:  2014-02-02       Impact factor: 2.031

3.  Intravitreal bevacizumab for choroidal neovascularization secondary to non-age-related macular degeneration.

Authors:  Masoud Salehipour; Nasser Vafi; Azade Doozande; Mehdi Yaseri
Journal:  J Ophthalmic Vis Res       Date:  2010-01
  3 in total

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