Literature DB >> 18556869

Idiopathic fibrosis of the quadriceps muscle: a case report with magnetic resonance imaging and pathological findings.

Rachawan Suksathien1.   

Abstract

BACKGROUND: Idiopathic fibrosis of the quadriceps muscle can be defined as progressive loss of knee flexion due to fibrosis within the muscle developed in early childhood. A few cases have been reported, but these did not detail the MRI and pathological findings. MATERIAL AND
METHOD: A 28-year-old woman presented with difficulty in sitting and inability to bend both knees completely. The clinical evaluation, radiological examination, MRI, treatment and muscle pathology were demonstrated
RESULTS: The knee flexions were limited in both knee joints. Magnetic resonance imaging of both thighs showed marked quadriceps muscle atrophy with fat infiltration and fibrous band. Intraoperative findings demonstrated fibrous band of vastus intermedius and vastus lateralis muscles which correlated with the MRI. The histological findings also revealed loose connective tissue separating muscle fibers and large fibrous band Z-plasty and release of the fibrotic muscles were performed. The result of the surgery was good
CONCLUSION: This is the first report to correlate MRI and pathological findings of idiopathic fibrosis of the quadriceps muscle. Late diagnosis and treatment may produce irreversible changes of femoral condyles and patella. Clinical awareness with history, physical examination and radiographic findings which included MRI help in confirming the diagnosis and demonstrating the extent of fibrosis before surgery.

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Year:  2008        PMID: 18556869

Source DB:  PubMed          Journal:  J Med Assoc Thai        ISSN: 0125-2208


  1 in total

1.  Increased expression of collagens, transforming growth factor-beta1, and -beta3 in gluteal muscle contracture.

Authors:  Chen-Guang Zhao; Xi-Jing He; Bin Lu; Hao-Peng Li; An-Jing Kang
Journal:  BMC Musculoskelet Disord       Date:  2010-01-25       Impact factor: 2.362

  1 in total

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