Literature DB >> 18556768

"MGMT for pt mgmt": is methylguanine-DNA methyltransferase testing ready for patient management?

A John Iafrate1, David N Louis.   

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Year:  2008        PMID： 18556768      PMCID： PMC2438198          DOI： 10.2353/jmoldx.2008.080043

Source DB:  PubMed          Journal:  J Mol Diagn        ISSN： 1525-1578            Impact factor:   5.568


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  25 in total

Review 1.  DNA methylation: a profile of methods and applications.

Authors:  Mario F Fraga; Manel Esteller
Journal:  Biotechniques       Date:  2002-09       Impact factor: 1.993

Review 2.  MGMT: its role in cancer aetiology and cancer therapeutics.

Authors:  Stanton L Gerson
Journal:  Nat Rev Cancer       Date:  2004-04       Impact factor: 60.716

3.  CpG island methylator phenotype in colorectal cancer.

Authors:  M Toyota; N Ahuja; M Ohe-Toyota; J G Herman; S B Baylin; J P Issa
Journal:  Proc Natl Acad Sci U S A       Date:  1999-07-20       Impact factor: 11.205

4.  Predicting lung cancer by detecting aberrant promoter methylation in sputum.

Authors:  W A Palmisano; K K Divine; G Saccomanno; F D Gilliland; S B Baylin; J G Herman; S A Belinsky
Journal:  Cancer Res       Date:  2000-11-01       Impact factor: 12.701

5.  O6-methylguanine-DNA methyltransferase activity in adult gliomas: relation to patient and tumor characteristics.

Authors:  J R Silber; M S Bobola; S Ghatan; A Blank; D D Kolstoe; M S Berger
Journal:  Cancer Res       Date:  1998-03-01       Impact factor: 12.701

6.  Inactivation of the DNA repair gene O6-methylguanine-DNA methyltransferase by promoter hypermethylation is a common event in primary human neoplasia.

Authors:  M Esteller; S R Hamilton; P C Burger; S B Baylin; J G Herman
Journal:  Cancer Res       Date:  1999-02-15       Impact factor: 12.701

7.  Molecular mechanisms associated with chromosomal and microsatellite instability in sporadic glioblastoma multiforme.

Authors:  Ramon Martinez; Hans-K Schackert; Jens Plaschke; Gustavo Baretton; Hella Appelt; Gabriele Schackert
Journal:  Oncology       Date:  2004       Impact factor: 2.935

8.  Association of breast cancer DNA methylation profiles with hormone receptor status and response to tamoxifen.

Authors:  Martin Widschwendter; Kimberly D Siegmund; Hannes M Müller; Heidi Fiegl; Christian Marth; Elisabeth Müller-Holzner; Peter A Jones; Peter W Laird
Journal:  Cancer Res       Date:  2004-06-01       Impact factor: 12.701

9.  Validation of real-time methylation-specific PCR to determine O6-methylguanine-DNA methyltransferase gene promoter methylation in glioma.

Authors:  Ilse Vlassenbroeck; Stéphane Califice; Annie-Claire Diserens; Eugenia Migliavacca; Josef Straub; Ivano Di Stefano; Fabrice Moreau; Marie-France Hamou; Isabelle Renard; Mauro Delorenzi; Bruno Flamion; James DiGuiseppi; Katja Bierau; Monika E Hegi
Journal:  J Mol Diagn       Date:  2008-06-13       Impact factor: 5.568

10.  Graded methylation in the promoter and body of the O6-methylguanine DNA methyltransferase (MGMT) gene correlates with MGMT expression in human glioma cells.

Authors:  J F Costello; B W Futscher; K Tano; D M Graunke; R O Pieper
Journal:  J Biol Chem       Date:  1994-06-24       Impact factor: 5.157
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  4 in total

Review 1.  Molecular pathology in adult gliomas: diagnostic, prognostic, and predictive markers.

Authors:  Michael Jansen; Stephen Yip; David N Louis
Journal:  Lancet Neurol       Date:  2010-07       Impact factor: 44.182

2.  MethMarker: user-friendly design and optimization of gene-specific DNA methylation assays.

Authors:  Peter Schüffler; Thomas Mikeska; Andreas Waha; Thomas Lengauer; Christoph Bock
Journal:  Genome Biol       Date:  2009-10-05       Impact factor: 13.583

Review 3.  O6-Methylguanine-DNA methyltransferase protein expression by immunohistochemistry in brain and non-brain systemic tumours: systematic review and meta-analysis of correlation with methylation-specific polymerase chain reaction.

Authors:  Marta Brell; Javier Ibáñez; Avelina Tortosa
Journal:  BMC Cancer       Date:  2011-01-26       Impact factor: 4.430

4.  Extent of MGMT promoter methylation correlates with outcome in glioblastomas given temozolomide and radiotherapy.

Authors:  J Dunn; A Baborie; F Alam; K Joyce; M Moxham; R Sibson; D Crooks; D Husband; A Shenoy; A Brodbelt; H Wong; T Liloglou; B Haylock; C Walker
Journal:  Br J Cancer       Date:  2009-06-16       Impact factor: 7.640
  4 in total

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