Literature DB >> 18556722

How does genotype define phenotype? Microphysiology of a tropomyosin mutation in situ shows the limitations of reductionism.

Steven Marston1.   

Abstract

Mesh：

Substances：

Year:  2008        PMID： 18556722      PMCID： PMC2517211          DOI： 10.1113/jphysiol.2008.155606

Source DB:  PubMed          Journal:  J Physiol        ISSN： 0022-3751            Impact factor:   5.182


× No keyword cloud information.
  5 in total

1.  Deciphering the design of the tropomyosin molecule.

Authors:  J H Brown; K H Kim; G Jun; N J Greenfield; R Dominguez; N Volkmann; S E Hitchcock-DeGregori; C Cohen
Journal:  Proc Natl Acad Sci U S A       Date:  2001-07-03       Impact factor: 11.205

Review 2.  What is the role of tropomyosin in the regulation of muscle contraction?

Authors:  S V Perry
Journal:  J Muscle Res Cell Motil       Date:  2003       Impact factor: 2.698

3.  Dilated cardiomyopathy mutations in three thin filament regulatory proteins result in a common functional phenotype.

Authors:  Mahmooda Mirza; Steven Marston; Ruth Willott; Christopher Ashley; Jens Mogensen; William McKenna; Paul Robinson; Charles Redwood; Hugh Watkins
Journal:  J Biol Chem       Date:  2005-05-27       Impact factor: 5.157

4.  Defective regulation of contractile function in muscle fibres carrying an E41K beta-tropomyosin mutation.

Authors:  Julien Ochala; Meishan Li; Monica Ohlsson; Anders Oldfors; Lars Larsson
Journal:  J Physiol       Date:  2008-04-17       Impact factor: 5.182

5.  The effect of mutations in alpha-tropomyosin (E40K and E54K) that cause familial dilated cardiomyopathy on the regulatory mechanism of cardiac muscle thin filaments.

Authors:  Mahmooda Mirza; Paul Robinson; Elena Kremneva; O'neal Copeland; Olga Nikolaeva; Hugh Watkins; Dimitry Levitsky; Charles Redwood; Mohammed El-Mezgueldi; Steven Marston
Journal:  J Biol Chem       Date:  2007-03-13       Impact factor: 5.157
  5 in total
  1 in total

1.  Phosphorylated HSP20 modulates the association of thin-filament binding proteins: caldesmon with tropomyosin in colonic smooth muscle.

Authors:  Sita Somara; Robert R Gilmont; Saranyaraajan Varadarajan; Khalil N Bitar
Journal:  Am J Physiol Gastrointest Liver Physiol       Date:  2010-09-09       Impact factor: 4.052
  1 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.