BACKGROUND AND PURPOSE: To quantify respiratory motion of the vocal cords during normal respiration using 4D-CT. The final goal is to develop a technique for single vocal cord irradiation (SVCI) in early glottic carcinoma. Sparing the non-involved cord and surrounding structures has the potential to preserve voice quality and allow re-irradiation of recurrent and second primary tumors. MATERIAL AND METHODS: Four-dimensional CTs of 1mm slice thickness from 10 early glottic carcinoma patients were acquired. The lateral dimensions of the air gap separating the vocal cords were measured anteriorly, at mid-level and posteriorly at each phase of the 4D-CTs. The corresponding anterior-posterior gaps were similarly measured. Cranio-caudal vocal cords movements during breathing were derived from the shifts of the arythenoids. RESULTS: The population-averaged mean gap size+/-the corresponding standard deviation due to breathing (SD(B)) for the lateral gaps was 5.8+/-0.7mm anteriorly, 8.7+/-0.9mm at mid-level, and 11.0+/-1.3mm posteriorly. Anterior-posterior gap values were 21.7+/-0.7mm, while cranio-caudal shift SD(B) was 0.8mm. CONCLUSION: Vocal cords breathing motions were found to be small relative to their separation. Hence, breathing motion does not seem to be a limiting factor for SVCI.
BACKGROUND AND PURPOSE: To quantify respiratory motion of the vocal cords during normal respiration using 4D-CT. The final goal is to develop a technique for single vocal cord irradiation (SVCI) in early glottic carcinoma. Sparing the non-involved cord and surrounding structures has the potential to preserve voice quality and allow re-irradiation of recurrent and second primary tumors. MATERIAL AND METHODS: Four-dimensional CTs of 1mm slice thickness from 10 early glottic carcinomapatients were acquired. The lateral dimensions of the air gap separating the vocal cords were measured anteriorly, at mid-level and posteriorly at each phase of the 4D-CTs. The corresponding anterior-posterior gaps were similarly measured. Cranio-caudal vocal cords movements during breathing were derived from the shifts of the arythenoids. RESULTS: The population-averaged mean gap size+/-the corresponding standard deviation due to breathing (SD(B)) for the lateral gaps was 5.8+/-0.7mm anteriorly, 8.7+/-0.9mm at mid-level, and 11.0+/-1.3mm posteriorly. Anterior-posterior gap values were 21.7+/-0.7mm, while cranio-caudal shift SD(B) was 0.8mm. CONCLUSION: Vocal cords breathing motions were found to be small relative to their separation. Hence, breathing motion does not seem to be a limiting factor for SVCI.
Authors: David I Rosenthal; Clifton D Fuller; Jerry L Barker; Bryan Mason; John A Garcia; Jan S Lewin; F Christopher Holsinger; C Richard Stasney; Steven J Frank; David L Schwartz; William H Morrison; Adam S Garden; K Kian Ang Journal: Int J Radiat Oncol Biol Phys Date: 2009-08-11 Impact factor: 7.038
Authors: Charles A Baron; Musaddiq J Awan; Abdallah S R Mohamed; Imad Akel; David I Rosenthal; G Brandon Gunn; Adam S Garden; Brandon A Dyer; Laurence Court; Parag R Sevak; Esengul Kocak-Uzel; Clifton D Fuller Journal: J Appl Clin Med Phys Date: 2014-01-08 Impact factor: 2.102
Authors: David L Schwartz; Alan Sosa; Stephen G Chun; Chiuxiong Ding; Xian-Jin Xie; Lucien A Nedzi; Robert D Timmerman; Baran D Sumer Journal: PLoS One Date: 2017-03-02 Impact factor: 3.240