Literature DB >> 18555720

Oxidized glycerophosphocholines as biologically active mediators for ultraviolet radiation-mediated effects.

Raymond L Konger1, Gopal K Marathe, Yongxue Yao, Qiwei Zhang, Jeffrey B Travers.   

Abstract

Ultraviolet light radiation (UVR) has profound effects upon human skin. Yet, the exact targets for UVR are unclear. Inasmuch as UVR is a known pro-oxidative stressor, one potential target for UVR could be oxidatively modified glycerophosphocholines (GPC). Importantly, recent studies demonstrate that these oxidized GPCs (ox-GPC) are potent agonists for the platelet-activating factor receptor and peroxisome proliferator-activated receptor gamma. This review discusses these new biologically active lipids and their down-stream receptor targets that provide a unique system of biosensors for detecting and responding to UVR photo-oxidation.

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Year:  2008        PMID： 18555720      PMCID： PMC3343742          DOI： 10.1016/j.prostaglandins.2008.04.002

Source DB:  PubMed          Journal:  Prostaglandins Other Lipid Mediat        ISSN： 1098-8823            Impact factor:   3.072


  101 in total

1.  Cyclooxygenase-2 expression is critical for chronic UV-induced murine skin carcinogenesis.

Authors:  Susan M Fischer; Amy Pavone; Carol Mikulec; Robert Langenbach; Joyce E Rundhaug
Journal:  Mol Carcinog       Date:  2007-05       Impact factor: 4.784

2.  Platelet-activating factor is crucial in psoralen and ultraviolet A-induced immune suppression, inflammation, and apoptosis.

Authors:  Peter Wolf; Dat X Nghiem; Jeffrey P Walterscheid; Scott Byrne; Yumi Matsumura; Yasuhiro Matsumura; Cora Bucana; Honnavara N Ananthaswamy; Stephen E Ullrich
Journal:  Am J Pathol       Date:  2006-09       Impact factor: 4.307

Review 3.  Thiazolidinediones: potential as therapeutics for psoriasis and perhaps other hyperproliferative skin disease.

Authors:  James Varani; Narasimharao Bhagavathula; Charles N Ellis; Harrihar A Pershadsingh
Journal:  Expert Opin Investig Drugs       Date:  2006-11       Impact factor: 6.206

4.  Apoptosis signal regulating kinase-1 connects reactive oxygen species to p38 MAPK-induced mitochondrial apoptosis in UVB-irradiated human keratinocytes.

Authors:  An Van Laethem; Kris Nys; Sofie Van Kelst; Sofie Claerhout; Hidenori Ichijo; Jackie R Vandenheede; Maria Garmyn; Patrizia Agostinis
Journal:  Free Radic Biol Med       Date:  2006-07-15       Impact factor: 7.376

5.  Hypoxia-inducible factor-1alpha, a key factor in the keratinocyte response to UVB exposure.

Authors:  Hamid Reza Rezvani; Sophie Dedieu; Sophie North; Francis Belloc; Rodrigue Rossignol; Thierry Letellier; Hubert de Verneuil; Alain Taïeb; Frédéric Mazurier
Journal:  J Biol Chem       Date:  2007-03-30       Impact factor: 5.157

Review 6.  Chronic inflammation and oxidative stress in the genesis and perpetuation of cancer: role of lipid peroxidation, DNA damage, and repair.

Authors:  Helmut Bartsch; Jagadeesan Nair
Journal:  Langenbecks Arch Surg       Date:  2006-08-15       Impact factor: 3.445

7.  Malignant transformation of DMBA/TPA-induced papillomas and nevi in the skin of mice selectively lacking retinoid-X-receptor alpha in epidermal keratinocytes.

Authors:  Arup Kumar Indra; Eduardo Castaneda; Maria Cristina Antal; Ming Jiang; Nadia Messaddeq; Xiangjun Meng; Christiane V Loehr; Patricio Gariglio; Shigeaki Kato; Walter Wahli; Béatrice Desvergne; Daniel Metzger; Pierre Chambon
Journal:  J Invest Dermatol       Date:  2007-02-15       Impact factor: 8.551

8.  Cyclooxygenase-2 inhibits UVB-induced apoptosis in mouse skin by activating the prostaglandin E2 receptors, EP2 and EP4.

Authors:  Kyung-Soo Chun; Jacqueline K Akunda; Robert Langenbach
Journal:  Cancer Res       Date:  2007-03-01       Impact factor: 12.701

9.  n-3 and n-6 polyunsaturated fatty acids induce the expression of COX-2 via PPARgamma activation in human keratinocyte HaCaT cells.

Authors:  Gérald Chêne; Marc Dubourdeau; Patricia Balard; Laure Escoubet-Lozach; Claudine Orfila; Antoine Berry; José Bernad; Marie-Françoise Aries; Marie Charveron; Bernard Pipy
Journal:  Biochim Biophys Acta       Date:  2007-03-16

10.  Dietary grape seed proanthocyanidins inhibit UVB-induced oxidative stress and activation of mitogen-activated protein kinases and nuclear factor-kappaB signaling in in vivo SKH-1 hairless mice.

Authors:  Som D Sharma; Syed M Meeran; Santosh K Katiyar
Journal:  Mol Cancer Ther       Date:  2007-03       Impact factor: 6.261
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  27 in total

1.  Platelet-activating factor receptor agonists mediate xeroderma pigmentosum A photosensitivity.

Authors:  Yongxue Yao; Kathleen A Harrison; Mohammed Al-Hassani; Robert C Murphy; Samin Rezania; Raymond L Konger; Jeffrey B Travers
Journal:  J Biol Chem       Date:  2012-02-01       Impact factor: 5.157

2.  Platelet-Activating Factor-Receptor and Tumor Immunity.

Authors:  Ravi P Sahu; Raymond L Konger; Jeffrey B Travers
Journal:  JSM Cell Dev Biol       Date:  2014-06-19

3.  The environmental stressor ultraviolet B radiation inhibits murine antitumor immunity through its ability to generate platelet-activating factor agonists.

Authors:  Ravi P Sahu; Matthew J Turner; Sonia C DaSilva; Badri M Rashid; Jesus A Ocana; Susan M Perkins; Raymond L Konger; Christopher E Touloukian; Mark H Kaplan; Jeffrey B Travers
Journal:  Carcinogenesis       Date:  2012-04-27       Impact factor: 4.944

4.  Ultraviolet B radiation of human skin generates platelet-activating factor receptor agonists.

Authors:  Jared B Travers; Damien Berry; Yongxue Yao; Qiaofang Yi; Raymond L Konger; Jeffrey B Travers
Journal:  Photochem Photobiol       Date:  2010-05-13       Impact factor: 3.421

5.  The peroxisome proliferator-activated receptor gamma system regulates ultraviolet B-induced prostaglandin e(2) production in human epidermal keratinocytes.

Authors:  Raymond L Konger; Kellie Clay Martel; Danielle Jernigan; Qiwei Zhang; Jeffrey B Travers
Journal:  PPAR Res       Date:  2010-05-19       Impact factor: 4.964

6.  Epidermal platelet-activating factor receptor activation and ultraviolet B radiation result in synergistic tumor necrosis factor-alpha production.

Authors:  Jay E Wolverton; Mohammed Al-Hassani; Yongxue Yao; Qiwei Zhang; Jeffrey B Travers
Journal:  Photochem Photobiol       Date:  2009-09-21       Impact factor: 3.421

7.  Cigarette smoke exposure inhibits contact hypersensitivity via the generation of platelet-activating factor agonists.

Authors:  Ravi P Sahu; Irina Petrache; Mary J Van Demark; Badri M Rashid; Jesus A Ocana; Yuxuan Tang; Qiaofang Yi; Matthew J Turner; Raymond L Konger; Jeffrey B Travers
Journal:  J Immunol       Date:  2013-01-25       Impact factor: 5.422

8.  Acute Ethanol Exposure Augments Low-Dose UVB-Mediated Systemic Immunosuppression via Enhanced Production of Platelet-Activating Factor Receptor Agonists.

Authors:  Jeffrey B Travers; Jonathan Weyerbacher; Jesus A Ocana; Christina Borchers; Christine M Rapp; Ravi P Sahu
Journal:  J Invest Dermatol       Date:  2019-01-23       Impact factor: 8.551

9.  Chemotherapeutic agents subvert tumor immunity by generating agonists of platelet-activating factor.

Authors:  Ravi P Sahu; Jesus A Ocana; Kathleen A Harrison; Matheus Ferracini; Christopher E Touloukian; Mohammed Al-Hassani; Louis Sun; Mathew Loesch; Robert C Murphy; Sandra K Althouse; Susan M Perkins; Paul J Speicher; Douglas S Tyler; Raymond L Konger; Jeffrey B Travers
Journal:  Cancer Res       Date:  2014-10-10       Impact factor: 12.701

10.  NF-E2-related factor 2 regulates the stress response to UVA-1-oxidized phospholipids in skin cells.

Authors:  Florian Gruber; Herbert Mayer; Barbara Lengauer; Veronika Mlitz; John M Sanders; Alexandra Kadl; Martin Bilban; Rainer de Martin; Oswald Wagner; Thomas W Kensler; Masayuki Yamamoto; Norbert Leitinger; Erwin Tschachler
Journal:  FASEB J       Date:  2009-08-31       Impact factor: 5.191
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