| Literature DB >> 18554956 |
João Eduardo Gomes-Filho1, Pedro Felício Estrada Bernabé, Mauro Juvenal Nery, José Arlindo Otoboni-Filho, Eloi Dezan-Júnior, Mariana Machado Teixeira de Moraes Costa, Max Douglas de Faria, Simone Watanabe, Alessandra Cristina Gomes.
Abstract
The aim of this study was to histopathologically examine the reaction of the connective tissue of rats to 2 calcium hydroxide-based sealers, Acroseal and Sealapex. Dentin tubes containing the materials and empty control tubes were implanted into the dorsal connective tissue of 36 Wistar albino rats. The animals were killed after 7 or 30 days, and the specimens were prepared for histologic analysis with hematoxylin and eosin, Von Kossa technique, and polarized light. Results were statistically analyzed using Kruskal-Wallis test. Both materials caused mild or moderate inflammatory reactions on the 7th day, but these reactions decreased by the 30th day with no significant difference at any time (P > .05). Mineralization of the subcutaneous tissue of the rats was observed only with Sealapex.Entities:
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Year: 2008 PMID： 18554956 DOI： 10.1016/j.tripleo.2008.03.030
Source DB: PubMed Journal: Oral Surg Oral Med Oral Pathol Oral Radiol Endod ISSN： 1079-2104