Literature DB >> 18554597

Relaxin increases elastase activity and protease inhibitors in smooth muscle cells from the myometrium compared with cells from leiomyomas.

Bertha Chen1, Yan Wen, Xiao Yun Yu, Mary Lake Polan.   

Abstract

We investigated the effect of relaxin on extracellular matrix remodeling in cultured myometrial compared with leiomyoma smooth muscle cells. Relaxin increases elastase activity and protease inhibitor expressions in myometrial smooth muscle cells, but no effect was observed in leiomyoma cells.

Entities:  

Mesh：

Substances：

Year:  2008        PMID： 18554597      PMCID： PMC2728012          DOI： 10.1016/j.fertnstert.2008.03.043

Source DB:  PubMed          Journal:  Fertil Steril        ISSN： 0015-0282            Impact factor:   7.329


  21 in total

1.  The frequency of uterine leiomyomas.

Authors:  S F Cramer; A Patel
Journal:  Am J Clin Pathol       Date:  1990-10       Impact factor: 2.493

2.  Relaxin increases secretion of tissue inhibitor of matrix metalloproteinase-1 and -2 during uterine and cervical growth and remodeling in the pig.

Authors:  Judy A Lenhart; Peter L Ryan; Kathleen M Ohleth; Stephen S Palmer; Carol A Bagnell
Journal:  Endocrinology       Date:  2002-01       Impact factor: 4.736

3.  Patterns of growth of uterine leiomyomas during pregnancy. A prospective longitudinal study.

Authors:  A Aharoni; A Reiter; D Golan; Y Paltiely; M Sharf
Journal:  Br J Obstet Gynaecol       Date:  1988-05

4.  Relaxin positively regulates matrix metalloproteinase expression in human lower uterine segment fibroblasts using a tyrosine kinase signaling pathway.

Authors:  S Palejwala; D E Stein; G Weiss; B P Monia; D Tortoriello; L T Goldsmith
Journal:  Endocrinology       Date:  2001-08       Impact factor: 4.736

Review 5.  Leiomyomata uteri: hormonal and molecular determinants of growth.

Authors:  Richard Enrique Blake
Journal:  J Natl Med Assoc       Date:  2007-10       Impact factor: 1.798

6.  Differences in estrogen modulation of tissue inhibitor of matrix metalloproteinase-1 and matrix metalloproteinase-1 expression in cultured fibroblasts from continent and incontinent women.

Authors:  Bertha Chen; Yan Wen; Hongbo Wang; Mary Lake Polan
Journal:  Am J Obstet Gynecol       Date:  2003-07       Impact factor: 8.661

7.  Expression of connexin-43 in human myometrium and leiomyoma.

Authors:  J Andersen; E Grine; C L Eng; K Zhao; R L Barbieri; J C Chumas; P R Brink
Journal:  Am J Obstet Gynecol       Date:  1993-11       Impact factor: 8.661

Review 8.  Sex steroidal regulation of uterine leiomyoma growth and apoptosis.

Authors:  T Maruo; N Ohara; J Wang; H Matsuo
Journal:  Hum Reprod Update       Date:  2004 May-Jun       Impact factor: 15.610

9.  Matrix metalloproteinases of human leiomyoma in various stages of tumor growth.

Authors:  Małgorzata Wolańska; Krzysztof Sobolewski; Edward Bańkowski; Stefan Jaworski
Journal:  Gynecol Obstet Invest       Date:  2004-03-05       Impact factor: 2.031

10.  Different proliferative and apoptotic activity in peripheral versus central parts of human uterine leiomyomas.

Authors:  Vladimir Bourlev; Stanislav Pavlovitch; Denis Stygar; Nikolai Volkov; Bo Lindblom; Matts Olovsson
Journal:  Gynecol Obstet Invest       Date:  2003       Impact factor: 2.031
View more
  1 in total

1.  Trends in serum relaxin concentration among elite collegiate female athletes.

Authors:  Jason L Dragoo; Tiffany N Castillo; Tatiana A Korotkova; Ashleigh C Kennedy; Hyeon Joo Kim; Dennis R Stewart
Journal:  Int J Womens Health       Date:  2011-01-19
  1 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.