| Literature DB >> 18554555 |
Denis Chatelain1, Nassima Mokrani, Jean-François Fléjou.
Abstract
Microscopic colitis is currently classified as a chronic inflammatory bowel disorder and encompasses two entities: lymphocytic colitis and collagenous colitis. Patients with microscopic colitis present with a well-tolerated chronic watery diarrhea, sometimes with abdominal pain. Colonoscopy is normal. Diagnosis of microscopic colitis is established by histologic examination of colonic biopsies, showing a thickened subsurface collagen band higher than 10 microm in collagenous colitis, and an increased number of surface intra-epithelial lymphocytes higher than 20 lymphocytes per 100 epithelial cells in lymphocytic colitis. Causes of microscopic colitis are still unknown, although a drug-induced etiology is found in some cases. Patients are usually treated with budesonide but recurrences are frequent.Entities:
Mesh:
Year: 2007 PMID: 18554555 DOI: 10.1016/S0242-6498(07)71417-7
Source DB: PubMed Journal: Ann Pathol ISSN: 0242-6498 Impact factor: 0.407