Action of low-intensity laser radiation on Escherichia coli.

The review deals with quantitative laws of monochromatic visible light action on the cellular level, as well as with the primary photoacceptors and possible light signal transduction chains in bacterial cell Escherichia coli WP2 trp-. Experiments described in this paper are a part of experimental work performed for explaining the molecular mechanism of low-intensity laser therapy. The existence of certain parameters of light (dose, intensity, pulse repetition rate, monochromaticity within the absorbtion bandwidth of biomolecules) for stimulation of E. coli WP2 metabolism has been established. The necessity for a certain physiological state of bacteria cells sensitive to irradiation has been shown. The sensitivity of bacteria to irradiation with monochromatic visible light has been proposed to be a delta pH-dependent genetic process.