Literature DB >> 18551932

Pattern of potential drug-drug interactions in diabetic out-patients in a tertiary care teaching hospital in Nepal.

K U Dinesh1, P Subish, M Pranaya, P Ravi Shankar, S K Anil, B Durga.   

Abstract

A prospective study was conducted at Manipal Teaching Hospital, Pokhara, Nepal to identify and analyze the pattern of the potential DDIs (drug-drug interaction) in diabetes patients. A total of 182 patients who were prescribed 685 drugs (average, 3.76 drugs per prescription) were enrolled. Patients 51 to 60 years of age had a higher risk [43 patients, or (23.6%)] of developing DDIs. It was found that 174 (92.1%) of the potential DDIs were of "moderate" severity. Cardiovascular drugs carried a risk of DDIs (187 drugs, or 49.5%). The most common potential DDI observed was between metformin and enalapril (n = 64).

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Year:  2007        PMID： 18551932

Source DB:  PubMed          Journal:  Med J Malaysia        ISSN： 0300-5283


  8 in total

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