| Literature DB >> 18551353 |
Mitsuteru Akahoshi1, Kumiko Aizawa, Shuji Nagano, Hisako Inoue, Atsushi Sadanaga, Yojiro Arinobu, Hiroaki Niiro, Hitoshi Nakashima.
Abstract
We report the case of a 38-year-old female patient with systemic lupus erythematosus (SLE) who developed acquired hemophilia caused by factor VIII (FVIII) inhibitors. She manifested spontaneous bleeding symptoms such as ecchymoses and hematuria. Laboratory findings showed an isolated prolongation of the activated partial thromboplastin time, reduced FVIII activity, and a high titer of FVIII inhibitors. She was successfully treated with oral predonisolone and cyclosporine in combination with steroid and cyclophosphamide pulse therapy.Entities:
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Year: 2008 PMID： 18551353 DOI： 10.1007/s10165-008-0084-6
Source DB: PubMed Journal: Mod Rheumatol ISSN： 1439-7595 Impact factor: 3.023