Literature DB >> 18551266

The expanding universe of hypoxia.

Huafeng Zhang1, Gregg L Semenza.   

Abstract

Reduced oxygen availability (hypoxia) is sensed and transduced into changes in the activity or expression of cellular macromolecules. These responses impact on virtually all areas of biology and medicine. In this meeting report, we summarize major developments in the field that were presented at the 2008 Keystone Symposium on Cellular, Physiological, and Pathogenic Responses to Hypoxia.

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Year:  2008        PMID: 18551266      PMCID: PMC2720566          DOI: 10.1007/s00109-008-0364-9

Source DB:  PubMed          Journal:  J Mol Med (Berl)        ISSN: 0946-2716            Impact factor:   4.599


  49 in total

1.  Hypoxia requires notch signaling to maintain the undifferentiated cell state.

Authors:  Maria V Gustafsson; Xiaowei Zheng; Teresa Pereira; Katarina Gradin; Shaobo Jin; Johan Lundkvist; Jorge L Ruas; Lorenz Poellinger; Urban Lendahl; Maria Bondesson
Journal:  Dev Cell       Date:  2005-11       Impact factor: 12.270

2.  Neuronal apoptosis linked to EglN3 prolyl hydroxylase and familial pheochromocytoma genes: developmental culling and cancer.

Authors:  Sungwoo Lee; Eijiro Nakamura; Haifeng Yang; Wenyi Wei; Michelle S Linggi; Mini P Sajan; Robert V Farese; Robert S Freeman; Bruce D Carter; William G Kaelin; Susanne Schlisio
Journal:  Cancer Cell       Date:  2005-08       Impact factor: 31.743

3.  Regulation of protein synthesis by hypoxia via activation of the endoplasmic reticulum kinase PERK and phosphorylation of the translation initiation factor eIF2alpha.

Authors:  Constantinos Koumenis; Christine Naczki; Marianne Koritzinsky; Sally Rastani; Alan Diehl; Nahum Sonenberg; Antonis Koromilas; Bradly G Wouters
Journal:  Mol Cell Biol       Date:  2002-11       Impact factor: 4.272

4.  Hypoxia alters gene expression in human neuroblastoma cells toward an immature and neural crest-like phenotype.

Authors:  Annika Jögi; Ingrid Øra; Helén Nilsson; Asa Lindeheim; Yuichi Makino; Lorenz Poellinger; Håkan Axelson; Sven Påhlman
Journal:  Proc Natl Acad Sci U S A       Date:  2002-05-14       Impact factor: 11.205

5.  Glomerular-specific alterations of VEGF-A expression lead to distinct congenital and acquired renal diseases.

Authors:  Vera Eremina; Manish Sood; Jody Haigh; András Nagy; Ginette Lajoie; Napoleone Ferrara; Hans-Peter Gerber; Yamato Kikkawa; Jeffrey H Miner; Susan E Quaggin
Journal:  J Clin Invest       Date:  2003-03       Impact factor: 14.808

Review 6.  Mammalian target of rapamycin as a therapeutic target in oncology.

Authors:  Robert T Abraham; Christina H Eng
Journal:  Expert Opin Ther Targets       Date:  2008-02       Impact factor: 6.902

7.  Redistribution of intracellular oxygen in hypoxia by nitric oxide: effect on HIF1alpha.

Authors:  Thilo Hagen; Cormac T Taylor; Francis Lam; Salvador Moncada
Journal:  Science       Date:  2003-12-12       Impact factor: 47.728

8.  Endogenous NO regulates superoxide production at low oxygen concentrations by modifying the redox state of cytochrome c oxidase.

Authors:  Miriam Palacios-Callender; Marisol Quintero; Veronica S Hollis; Roger J Springett; Salvador Moncada
Journal:  Proc Natl Acad Sci U S A       Date:  2004-05-10       Impact factor: 11.205

9.  Hypoxia-inducible factor 1 is a basic-helix-loop-helix-PAS heterodimer regulated by cellular O2 tension.

Authors:  G L Wang; B H Jiang; E A Rue; G L Semenza
Journal:  Proc Natl Acad Sci U S A       Date:  1995-06-06       Impact factor: 11.205

10.  Mast cells mediate the microvascular inflammatory response to systemic hypoxia.

Authors:  Dawn R S Steiner; Norberto C Gonzalez; John G Wood
Journal:  J Appl Physiol (1985)       Date:  2002-09-20
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  5 in total

1.  Hypoxia elicits broad and systematic changes in protein subcellular localization.

Authors:  Robert Michael Henke; Ranita Ghosh Dastidar; Ajit Shah; Daniela Cadinu; Xiao Yao; Jagmohan Hooda; Li Zhang
Journal:  Am J Physiol Cell Physiol       Date:  2011-07-13       Impact factor: 4.249

2.  VHL inactivation induces HEF1 and Aurora kinase A.

Authors:  Jianyong Xu; Huapeng Li; Bo Wang; Yan Xu; Jiayin Yang; Xiaofei Zhang; Sarah K Harten; Deepa Shukla; Patrick H Maxwell; Duanqing Pei; Miguel A Esteban
Journal:  J Am Soc Nephrol       Date:  2010-09-23       Impact factor: 10.121

3.  Deletion of a subgroup of ribosome-related genes minimizes hypoxia-induced changes and confers hypoxia tolerance.

Authors:  Ajit N Shah; Daniela Cadinu; R Michael Henke; Xiantong Xin; Ranita Ghosh Dastidar; Li Zhang
Journal:  Physiol Genomics       Date:  2011-05-17       Impact factor: 3.107

4.  A novel approach for reliable microarray analysis of microdissected tumor cells from formalin-fixed and paraffin-embedded colorectal cancer resection specimens.

Authors:  Silke Lassmann; Clemens Kreutz; Anja Schoepflin; Ulrich Hopt; Jens Timmer; Martin Werner
Journal:  J Mol Med (Berl)       Date:  2008-12-06       Impact factor: 4.599

5.  The nuclear localization of SWI/SNF proteins is subjected to oxygen regulation.

Authors:  Ranita Ghosh Dastidar; Jagmohan Hooda; Ajit Shah; Thai M Cao; Robert Michael Henke; Li Zhang
Journal:  Cell Biosci       Date:  2012-08-29       Impact factor: 7.133

  5 in total

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