Literature DB >> 18550411

Impact of visceral adipose tissue on liver metabolism. Part I: heterogeneity of adipose tissue and functional properties of visceral adipose tissue.

M Lafontan1, J Girard.   

Abstract

Excess visceral adipose tissue is associated with anomalies of blood glucose homoeostasis, elevation of plasma triglycerides and low high-density lipoprotein cholesterol that contribute to the later appearance of type 2 diabetes and cardiovascular syndromes. Visceral adipose tissue releases a large amount of free fatty acids and hormones/cytokines in the portal vein that are delivered to the liver, and interact with hepatocytes and various immune cells in the liver. The functional characteristics of visceral adipose tissue will be compared with subcutaneous adipose tissue to clarify the major mechanisms affecting free fatty acid metabolism and cytokine production.

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Year:  2008        PMID： 18550411     DOI： 10.1016/j.diabet.2008.04.001

Source DB:  PubMed          Journal:  Diabetes Metab        ISSN： 1262-3636            Impact factor:   6.041


  38 in total

1.  Surgical removal of omental fat does not improve insulin sensitivity and cardiovascular risk factors in obese adults.

Authors:  Elisa Fabbrini; Robyn A Tamboli; Faidon Magkos; Pamela A Marks-Shulman; Aaron W Eckhauser; William O Richards; Samuel Klein; Naji N Abumrad
Journal:  Gastroenterology       Date:  2010-05-07       Impact factor: 22.682

2.  Mesodermal developmental gene Tbx15 impairs adipocyte differentiation and mitochondrial respiration.

Authors:  Stephane Gesta; Olivier Bezy; Marcelo A Mori; Yazmin Macotela; Kevin Y Lee; C Ronald Kahn
Journal:  Proc Natl Acad Sci U S A       Date:  2011-01-31       Impact factor: 11.205

3.  Estrogens prevent metabolic dysfunctions induced by circadian disruptions in female mice.

Authors:  Liangru Zhu; Fang Zou; Yongjie Yang; Pingwen Xu; Kenji Saito; Antentor Othrell Hinton; Xiaofeng Yan; Hongfang Ding; Qi Wu; Makoto Fukuda; Zheng Sun; Qingchun Tong; Yong Xu
Journal:  Endocrinology       Date:  2015-03-25       Impact factor: 4.736

4.  Distinct hypothalamic neurons mediate estrogenic effects on energy homeostasis and reproduction.

Authors:  Yong Xu; Thekkethil P Nedungadi; Liangru Zhu; Nasim Sobhani; Boman G Irani; Kathryn E Davis; Xiaorui Zhang; Fang Zou; Lana M Gent; Lisa D Hahner; Sohaib A Khan; Carol F Elias; Joel K Elmquist; Deborah J Clegg
Journal:  Cell Metab       Date:  2011-10-05       Impact factor: 27.287

5.  Proteasomal degradation of retinoid X receptor alpha reprograms transcriptional activity of PPARgamma in obese mice and humans.

Authors:  Bruno Lefebvre; Yacir Benomar; Aurore Guédin; Audrey Langlois; Nathalie Hennuyer; Julie Dumont; Emmanuel Bouchaert; Catherine Dacquet; Luc Pénicaud; Louis Casteilla; Francois Pattou; Alain Ktorza; Bart Staels; Philippe Lefebvre
Journal:  J Clin Invest       Date:  2010-04-01       Impact factor: 14.808

Review 6.  Altered adipose tissue and adipocyte function in the pathogenesis of metabolic syndrome.

Authors:  C Ronald Kahn; Guoxiao Wang; Kevin Y Lee
Journal:  J Clin Invest       Date:  2019-10-01       Impact factor: 14.808

Review 7.  Epoxyeicosatrienoic acids and heme oxygenase-1 interaction attenuates diabetes and metabolic syndrome complications.

Authors:  Angela Burgess; Luca Vanella; Lars Bellner; Michal L Schwartzman; Nader G Abraham
Journal:  Prostaglandins Other Lipid Mediat       Date:  2011-11-15       Impact factor: 3.072

Review 8.  Revisiting the metabolic syndrome: the emerging role of aquaglyceroporins.

Authors:  Inês Vieira da Silva; Joana S Rodrigues; Irene Rebelo; Joana P G Miranda; Graça Soveral
Journal:  Cell Mol Life Sci       Date:  2018-02-20       Impact factor: 9.261

9.  Heme oxygenase-1 induction remodels adipose tissue and improves insulin sensitivity in obesity-induced diabetic rats.

Authors:  Angelique Nicolai; Ming Li; Dong Hyun Kim; Stephen J Peterson; Luca Vanella; Vincenzo Positano; Amalia Gastaldelli; Rita Rezzani; Luigi F Rodella; George Drummond; Claudia Kusmic; Antonio L'Abbate; Attallah Kappas; Nader G Abraham
Journal:  Hypertension       Date:  2009-01-26       Impact factor: 10.190

Review 10.  Perspective: Does brown fat protect against diseases of aging?

Authors:  Mark P Mattson
Journal:  Ageing Res Rev       Date:  2009-12-05       Impact factor: 10.895
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