Literature DB >> 18549975

A perspective of publicly accessible/open-access chemistry databases.

Antony J Williams1.   

Abstract

The Internet has spawned access to unprecedented levels of information. For chemists the increasing number of resources they can use to access chemistry-related information provides them a valuable path to discovery of information, one which was previously limited to commercial and therefore constrained resources. The diversity of information continues to expand at a dramatic rate and, coupled with an increasing awareness for quality, curation and improved tools for focused searches, chemists are now able to find valuable information within a few seconds using a few keystrokes. This shift to publicly available resources offers great promise to the benefits of science and society yet brings with it increasing concern from commercial entities. This article will discuss the benefits and disruptions associated with an increase in publicly available scientific resources.

Mesh:

Year:  2008        PMID: 18549975     DOI: 10.1016/j.drudis.2008.03.017

Source DB:  PubMed          Journal:  Drug Discov Today        ISSN: 1359-6446            Impact factor:   7.851


  14 in total

1.  Time for cooperation in health economics among the modelling community.

Authors:  Renée J G Arnold; Sean Ekins
Journal:  Pharmacoeconomics       Date:  2010       Impact factor: 4.981

2.  Reaching out to collaborators: crowdsourcing for pharmaceutical research.

Authors:  Sean Ekins; Antony J Williams
Journal:  Pharm Res       Date:  2010-01-27       Impact factor: 4.200

3.  Automatic vs. manual curation of a multi-source chemical dictionary: the impact on text mining.

Authors:  Kristina M Hettne; Antony J Williams; Erik M van Mulligen; Jos Kleinjans; Valery Tkachenko; Jan A Kors
Journal:  J Cheminform       Date:  2010-03-23       Impact factor: 5.514

4.  Essential metabolites of Mycobacterium tuberculosis and their mimics.

Authors:  Gyanu Lamichhane; Joel S Freundlich; Sean Ekins; Niluka Wickramaratne; Scott T Nolan; William R Bishai
Journal:  mBio       Date:  2011-02-01       Impact factor: 7.867

5.  Advances in structure elucidation of small molecules using mass spectrometry.

Authors:  Tobias Kind; Oliver Fiehn
Journal:  Bioanal Rev       Date:  2010-08-21

6.  Quantitative assessment of the expanding complementarity between public and commercial databases of bioactive compounds.

Authors:  Christopher Southan; Péter Várkonyi; Sorel Muresan
Journal:  J Cheminform       Date:  2009-07-06       Impact factor: 5.514

Review 7.  Defrosting the digital library: bibliographic tools for the next generation web.

Authors:  Duncan Hull; Steve R Pettifer; Douglas B Kell
Journal:  PLoS Comput Biol       Date:  2008-10-31       Impact factor: 4.475

8.  Ambiguity of non-systematic chemical identifiers within and between small-molecule databases.

Authors:  Saber A Akhondi; Sorel Muresan; Antony J Williams; Jan A Kors
Journal:  J Cheminform       Date:  2015-11-16       Impact factor: 5.514

9.  Iron behaving badly: inappropriate iron chelation as a major contributor to the aetiology of vascular and other progressive inflammatory and degenerative diseases.

Authors:  Douglas B Kell
Journal:  BMC Med Genomics       Date:  2009-01-08       Impact factor: 3.063

10.  A consensus yeast metabolic network reconstruction obtained from a community approach to systems biology.

Authors:  Markus J Herrgård; Neil Swainston; Paul Dobson; Warwick B Dunn; K Yalçin Arga; Mikko Arvas; Nils Blüthgen; Simon Borger; Roeland Costenoble; Matthias Heinemann; Michael Hucka; Nicolas Le Novère; Peter Li; Wolfram Liebermeister; Monica L Mo; Ana Paula Oliveira; Dina Petranovic; Stephen Pettifer; Evangelos Simeonidis; Kieran Smallbone; Irena Spasić; Dieter Weichart; Roger Brent; David S Broomhead; Hans V Westerhoff; Betül Kirdar; Merja Penttilä; Edda Klipp; Bernhard Ø Palsson; Uwe Sauer; Stephen G Oliver; Pedro Mendes; Jens Nielsen; Douglas B Kell
Journal:  Nat Biotechnol       Date:  2008-10       Impact factor: 54.908

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