| Literature DB >> 18549796 |
Chris B Moore1, Jenny P-Y Ting.
Abstract
Mitochondrial antiviral immunity involves the detection of viral RNA by intracellular pattern-recognition receptors (PRRs) belonging to the RIG-I-like helicase family. The convergence of these and other signaling molecules to the outer mitochondrial membrane results in the rapid induction of antiviral cytokines including type-1 interferon. Here, we discuss recent studies describing new molecules implicated in the regulation of this antiviral response.Mesh:
Substances:
Year: 2008 PMID: 18549796 DOI: 10.1016/j.immuni.2008.05.005
Source DB: PubMed Journal: Immunity ISSN: 1074-7613 Impact factor: 31.745