| Literature DB >> 18545331 |
Alex C-T Ko1, Mark Hewko, Michael G Sowa, Cecilia C S Dong, Blaine Cleghorn, Lin-P'ing Choo-Smith.
Abstract
A new fibre-optic coupled polarization-resolved Raman spectroscopic system was developed for simultaneous collection of orthogonally polarized Raman spectra in a single measurement. An application of detecting incipient dental caries based on changes observed in Raman polarization anisotropy was also demonstrated using the developed fibre-optic Raman spectroscopic system. The predicted reduction of polarization anisotropy in the Raman spectra of caries lesions was observed and the results were consistent with those reported previously with Raman microspectroscopy. The capability of simultaneous collection of parallel- and cross-polarized Raman spectra of tooth enamel in a single measurement and the improved laser excitation delivery through fibre-optics demonstrated in this new design illustrates its future clinical potential.Entities:
Mesh:
Year: 2008 PMID: 18545331 PMCID: PMC2435308 DOI: 10.1364/oe.16.006274
Source DB: PubMed Journal: Opt Express ISSN: 1094-4087 Impact factor: 3.894